Language and Sensory Neural Plasticity in the Superior Temporal Cortex of the Deaf

Neural Plasticity
Mochun QueLiping Wang

Abstract

Visual stimuli are known to activate the auditory cortex of deaf people, presenting evidence of cross-modal plasticity. However, the mechanisms underlying such plasticity are poorly understood. In this functional MRI study, we presented two types of visual stimuli, language stimuli (words, sign language, and lip-reading) and a general stimulus (checkerboard) to investigate neural reorganization in the superior temporal cortex (STC) of deaf subjects and hearing controls. We found that only in the deaf subjects, all visual stimuli activated the STC. The cross-modal activation induced by the checkerboard was mainly due to a sensory component via a feed-forward pathway from the thalamus and primary visual cortex, positively correlated with duration of deafness, indicating a consequence of pure sensory deprivation. In contrast, the STC activity evoked by language stimuli was functionally connected to both the visual cortex and the frontotemporal areas, which were highly correlated with the learning of sign language, suggesting a strong language component via a possible feedback modulation. While the sensory component exhibited specificity to features of a visual stimulus (e.g., selective to the form of words, bodies, or faces) and t...Continue Reading

References

Apr 25, 1997·Science·G A CalvertA S David
Jun 23, 1998·Current Opinion in Neurobiology·H J Neville, D Bavelier
Jan 29, 1999·Nature·H NishimuraT Kubo
Feb 17, 2000·Trends in Neurosciences·T KujalaR Näätänen
Jun 22, 2000·Trends in Cognitive Sciences·T AllisonG McCarthy
Jul 27, 2000·Human Brain Mapping·J L LancasterP T Fox
Dec 6, 2000·Proceedings of the National Academy of Sciences of the United States of America·L A PetittoA C Evans
Feb 24, 2001·Nature·D S LeeC S Kim
Sep 29, 2001·Science·P E DowningN Kanwisher
Nov 13, 2001·Nature Neuroscience·E M FinneyK R Dobkins
Mar 20, 2002·Neuropsychologia·Mairéad MacSweeneyMichael J Brammer
Jun 22, 2002·Brain : a Journal of Neurology·Mairéad MacSweeneyMichael J Brammer
Nov 8, 2002·Brain Research. Cognitive Brain Research·Brooke A ArmstrongTeresa V Mitchell
Feb 20, 2003·Journal of Cognitive Neuroscience·Gemma A Calvert, Ruth Campbell
Sep 10, 2003·Neuroreport·Eva M FinneyKaren R Dobkins
Apr 28, 2004·NeuroImage·Laurent Cohen, Stanislas Dehaene
Jul 28, 2004·NeuroImage·Mairéad MacSweeneyMichael J Brammer
Nov 2, 2005·Brain Research. Cognitive Brain Research·Nicole LambertzMichael Forsting
Nov 5, 2005·Journal of Cognitive Neuroscience·Ione FineKaren R Dobkins
May 30, 2006·Cerebral Cortex·Hyo-Jeong LeeDong Soo Lee
Sep 28, 2006·Brain : a Journal of Neurology·M E DoucetF Lepore
Nov 23, 2006·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Nancy Kanwisher, Galit Yovel
Apr 27, 2007·Brain Research·David CorinaAllen Braun
Oct 2, 2007·Brain : a Journal of Neurology·Hyo-Jeong LeeAnne-Lise Giraud
Feb 6, 2008·Neuropsychologia·Cheryl M CapekRuth Campbell
Sep 23, 2008·Trends in Cognitive Sciences·Mairéad MacSweeneyBencie Woll
Dec 24, 2008·Frontiers in Systems Neuroscience·Nikolaus KriegeskortePeter Bandettini
Nov 26, 2009·Nature Reviews. Neuroscience·Lotfi B Merabet, Alvaro Pascual-Leone
Dec 29, 2009·NeuroImage·Karl J Friston, Raymond J Dolan
Apr 17, 2010·Proceedings of the National Academy of Sciences of the United States of America·Silvia BremUlla Richardson
Sep 24, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Corinna KlingeChristian Büchel
May 20, 2011·Trends in Cognitive Sciences·Stanislas Dehaene, Laurent Cohen
Jan 11, 2012·Brain : a Journal of Neurology·Pascale SandmannStefan Debener
May 31, 2012·Brain Connectivity·Susan Whitfield-Gabrieli, Alfonso Nieto-Castanon
Jul 13, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthew K LeonardEric Halgren
Aug 22, 2012·The Journal of Laryngology and Otology·S Hassanzadeh
Feb 14, 2013·Nature Communications·Velia CardinBencie Woll
Sep 4, 2013·Neuroscience and Biobehavioral Reviews·C R LynessV Cardin
Mar 4, 2014·PloS One·Julia Campbell, Anu Sharma

❮ Previous
Next ❯

Methods Mentioned

BETA
RSA
cochlear implant
cochlear implants

Software Mentioned

Marsbar
SPM8
SimSun
WFU PickAtlas
RSA
SPM
CONN
Matlab
fMRI Functional Connectivity SPM

Related Concepts

Related Feeds

Brain Imaging of Neural Circuits

Neural circuits are groups of interconnected neurons which carry out specific functions when activated. Imaging these neural circuits allows researches to further elucidate their mechanisms and functions. Follow this feed to stay up to date on brain imaging of neural circuits.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Brain Imaging of Neural Circuits (MDS)

Neural circuits are groups of interconnected neurons which carry out specific functions when activated. Imaging these neural circuits allows researches to further elucidate their mechanisms and functions. Follow this feed to stay up to date on brain imaging of neural circuits.