Lanthanide terbium complex: synthesis, electrochemiluminescence (ECL) performance, and sensing application

The Analyst
Xia XuYinggui Zhu

Abstract

In this study, a new lanthanide terbium complex, Tb(pzda)3(NO3)3·nH2O, was synthesized by a hydrothermal method and characterized by Fourier transform infrared spectroscopy (FT-IR) and energy-dispersive X-ray spectroscopy (EDS). It was found that the as-synthesized Tb-complex exhibited good electrochemiluminescence (ECL) behavior in the presence of triethanolamine (TEOA) in a HAc-NaAc buffer solution on a glassy carbon electrode. The possible reaction mechanism has been discussed based on the fluorescence spectra and ECL spectra. For sensing applications, it was found that protocatechuic acid (PCA) had an obvious quenching effect on the ECL signal of the Tb-complex, and this resulted in a decreased ECL signal associated with the concentration of PCA. Therefore, a highly sensitive method for the detection of PCA was established with a linear range of 1.283 × 10-10 M to 3.845 × 10-4 M and a detection limit of 0.085 nM at an S/N ratio of 3. This novel ECL assay strategy with an outstanding ECL efficiency offers great potential for pharmaceutical analyses.

References

Sep 3, 2009·Journal of Agricultural and Food Chemistry·Chia-Yu LinMei-Chin Yin
Apr 5, 2011·Journal of Agricultural and Food Chemistry·Chia-Yu LinMei-Chin Yin
Jun 13, 2015·Environmental Science & Technology·Yaxin QinLizhi Zhang
Dec 14, 2016·Analytical Chemistry·Lingling LiJun-Jie Zhu
Apr 12, 2017·ACS Applied Materials & Interfaces·Huaping PengWei Chen
Jun 2, 2017·ACS Applied Materials & Interfaces·Wen-Rong CaiDan Shan
Jun 10, 2017·Journal of the American Chemical Society·Xiao TanGuizheng Zou
Dec 15, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Yali MaJun Shi
Dec 16, 2017·Analytical Chemistry·Cheng MaJun-Jie Zhu
Jan 23, 2018·Journal of the American Chemical Society·Shanshan LiuShu Wang
May 7, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yongbei ZhaoQin Wei

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Methods Mentioned

BETA
PCA
infrared spectroscopy
X-ray
Fluorescence

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