Lanthanum deposition corresponds to white lesions in the stomach

Pathology, Research and Practice
Masaya IwamuroHiroyuki Okada

Abstract

Although lanthanum deposition in the stomach has been most frequently reported to occur as white lesions, no study has investigated whether the white lesions observed during esophagogastroduodenoscopy are truly lanthanum-related. Here, we retrospectively investigated the amount of lanthanum in endoscopic biopsy specimens. We reviewed four patients showing gastric white spots or annular whitish mucosa in the gastric white lesions (Bw) and peripheral mucosa where the white substance was not endoscopically observed (Bp) during biopsy. We also reviewed three patients with diffuse whitish mucosa and three patients with no whitish lesions. We performed scanning electron microscopy and energy dispersive X-ray spectrometry to quantify the lanthanum elements (wt%) in the biopsy specimens. The amount of lanthanum in the Bw ranged from 0.15-0.31 wt%, whereas that of Bp was 0.00-0.13 wt%. The difference was statistically significant (P < 0.05). The amount of lanthanum in the Bw, endoscopically presented with white spots or annular whitish mucosa, was significantly higher than that of no whitish lesions (0.05-0.14 wt%, P < 0.05). The amount of lanthanum was also higher in the diffuse whitish mucosa (0.21-0.23 wt%) compared with no whitish l...Continue Reading

Citations

May 10, 2019·BMJ Case Reports·Yasutoshi Shiratori, Noriaki Oguri
Dec 24, 2019·Journal of UOEH·Kei YabukiMasanori Hisaoka
Apr 21, 2020·World Journal of Gastroenterology : WJG·Masaya IwamuroHiroyuki Okada
Feb 12, 2021·Archives of Pathology & Laboratory Medicine·Dipti M KaramchandaniChristina A Arnold

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