Laparoscopic adrenalectomy for adrenal tumours causing hypertension and for 'incidentalomas' of the adrenal on computerized tomography scanning

Clinical and Experimental Pharmacology & Physiology
J C RutherfordS A Klemm

Abstract

1. In a 19 month period from June 1993 to December 1994, 60 patients (mean age 54.8 +/- 1.5 years s.e.m.; 32 males, 28 females) underwent unilateral laparoscopic adrenalectomy by one of us (JCR) for the treatment of hypertension due to primary aldosteronism (n = 48), phaeochromocytoma (n = 3) and cortisol-producing adenoma (n = 1) or to remove adrenal massess incidentally discovered on abdominal computerized tomography scanning ('incidentaloma') performed for other reasons (seven adenomas without biochemical evidence of excessive steroid hormone or catecholamine secretion and one carcinoma autonomously producing cortisol). 2. Compared with conventional open procedures, laparoscopic adrenalectomy was associated with reduced recovery time and a low complication rate (one pulmonary embolus and one port site incisional hernia). 3. Operation time with experience approximates that of open procedures (60 min), but is significantly longer in obese than in non-obese patients, and in males than in females. 4. Patients with adrenal causes of hypertension were cured or significantly improved by laparoscopic unilateral adrenalectomy. 5. Because of our concern regarding malignant potential of incidentalomas and high patient acceptance of lap...Continue Reading

References

Dec 1, 1989·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·R D GordonW L Finn
May 1, 1993·The Journal of Urology·E HigashiharaY Aso

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Citations

May 12, 2004·Molecular and Cellular Endocrinology·Michael Stowasser, Richard D Gordon
Jul 19, 2002·ANZ Journal of Surgery·Stephen H PillingerStan Sidhu
Mar 3, 1998·Journal of the American College of Surgeons·J A van Heerden
Oct 19, 2004·World Journal of Surgery·Brian D SaundersPaul G Gauger
May 21, 2009·The Journal of Clinical Endocrinology and Metabolism·Bregje Van ZaaneDees P M Brandjes
Apr 15, 2004·Endocrine Reviews·Georg MansmannStefan R Bornstein
Jul 1, 1995·Journal of Endocrinological Investigation·R D Gordon

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