Laparoscopic gastrectomy for elderly patients with gastric cancer: A systematic review with meta-analysis

Medicine
Yu PanXue-Yong Zheng

Abstract

Laparoscopic gastrectomy (LG) has been widely applied in patients with gastric cancer (GC). However, the safety and application value of LG in elderly patients with GC was still unclear. In this study, we aimed to evaluate the feasibility and safety of LG for elderly patients with GC using the meta-analysis. Studies comparing elderly patients and nonelderly patients who underwent LG for GC were reviewed and collected from the PubMed, EBSCO, Cochrane Library, and EMBASE. Outcomes such as operative results, postoperative recovery, and morbidity were compared and analyzed. The Review Manager 5.3 was used to portray the weighted mean difference (WMD) and odds ratio (OR) with a 95% confidence interval (CI). Eleven observational studies with a total of 3275 patients were included. Compared with nonelderly patients, elderly patients had shorter operation time (WMD -10.46; 95% CI -17.06 to -3.86; P = .002), less retrieved lymph nodes (WMD -2.34; 95% CI -3.77 to -0.92; P = .001), delayed time to first flatus (WMD 0.31; 95% CI 0.10-0.51; P = .003), longer postoperative hospital stays (WMD 1.06; 95% CI 0.07-2.05; P = .04), higher risk for overall postoperative complication (OR 1.34; 95% CI 1.08-1.67; P = .009), nonsurgical postoperative c...Continue Reading

References

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Citations

Jul 15, 2018·Journal of Cellular and Molecular Medicine·Beibei ChenXiao-Bing Chen
Oct 23, 2019·Korean journal of anesthesiology·Byung-Gun Lim, Il-Ok Lee
Dec 13, 2018·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Michitaka HondaNaoki Hiki
Apr 27, 2021·Updates in Surgery·Stefano RauseiElisa Cassinotti
May 28, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Isacco MontroniTyler R Chesney

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Methods Mentioned

BETA
dissection

Software Mentioned

Review Manager
PRISMA

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