Laparoscopic Indocyanine Green Sentinel Lymph Node Mapping in Endometrial Cancer

Annals of Surgical Oncology
Andrea PapadiaMichael D Mueller

Abstract

In endometrial cancer (EMCA), indocyanine green (ICG) sentinel lymph node (SLN) mapping has been reported, mainly in conjunction with robotic surgery. We aimed to evaluate detection rates, sensitivity, and false negative (FN) rate of laparoscopic ICG SLN mapping in EMCA, and to evaluate differences in surgical outcomes between patients subjected to SLN biopsy only versus lymphadenectomy. A retrospective analysis of EMCA patients undergoing ICG SLN mapping ± pelvic (PLND) and/or para-aortic lymphadenectomy (PALND) was performed. Detection rates were calculated for the entire cohort. Sensitivity and FN rates were calculated for patients undergoing lymphadenectomy after SLN mapping, and surgical outcome was compared among patients undergoing SLN mapping only versus lymphadenectomy. Of 75 patients, 33 underwent SLN mapping and 42 underwent SLN mapping followed by PLND/PALND. Overall and bilateral detection rates were 96 % (72/75) and 88 % (66/75), respectively, and the median number of removed SLNs, pelvic non-SLNs (NSLN) and para-aortic NSLNs was 3, 27, and 19, respectively. With a FN rate of 8.3 %, only one patient had bilateral FN SLNs and a metastatic para-aortal NSLN. Estimated blood loss (EBL) and operative (OR) time were sig...Continue Reading

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Citations

Jun 20, 2016·Journal of Cancer Research and Clinical Oncology·Andrea PapadiaMichael D Mueller
Nov 7, 2016·Annals of Nuclear Medicine·Federica EliseiAlessandro Buda
Nov 23, 2016·American Journal of Obstetrics and Gynecology·Anna Jo Bodurtha SmithEdward J Tanner
May 10, 2017·Obstetrics and Gynecology·Kayla E IrelandPatrick S Ramsey
Jun 24, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Maria Luisa GasparriAndrea Papadia
Feb 13, 2019·Archives of Gynecology and Obstetrics·Tian WangZhengchen Guo
Oct 16, 2018·Minerva ginecologica·Andrea PapadiaMichael D Mueller
Aug 23, 2017·Journal of Cancer Research and Clinical Oncology·Andrea PapadiaMichael D Mueller
Jan 17, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Franziska SiegenthalerMichael D Mueller
Jul 3, 2017·Journal of Cancer Research and Clinical Oncology·Andrea PapadiaMichael D Mueller
Apr 25, 2018·Journal of Cancer Research and Clinical Oncology·Andrea PapadiaMichael D Mueller
Aug 5, 2018·Annals of Surgical Oncology·Jeffery ChakedisJohn E Phay
Jul 26, 2018·Journal of Cancer Research and Clinical Oncology·Andrea PapadiaMichael D Mueller
Sep 19, 2017·Current Treatment Options in Oncology·Stephanie A Sullivan, Emma C Rossi
Nov 22, 2018·Journal of Cancer Research and Clinical Oncology·Maria Luisa GasparriMichael D Mueller
Jul 8, 2020·Journal of Clinical Medicine·Virginia García PinedaIgnacio Zapardiel
Jul 1, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Maria Luisa GasparriAndrea Papadia
Jul 17, 2018·Archives of Gynecology and Obstetrics·Lijun Wang, Fang Liu
Jun 10, 2021·The Cochrane Database of Systematic Reviews·Hans NagarJo Morrison
Sep 9, 2020·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Rebecca NagarMamta Gupta
Oct 27, 2021·The Journal of Obstetrics and Gynaecology Research·María Nieves Cabezas PalaciosIgnacio Zapardiel Gutiérrez

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Methods Mentioned

BETA
fluorescence imaging
biopsy
hysterectomy
dissections

Software Mentioned

R
EMCA

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