Laparoscopic inguinal hernia repair in men with lightweight meshes may significantly impair sperm motility: a randomized controlled trial

Annals of Surgery
Ellen PeetersMarc Miserez

Abstract

To compare quality of life and fertility aspects after laparoscopic inguinal hernia repair in men using a heavyweight or lightweight mesh. The use of lightweight meshes in laparoscopic inguinal hernia repair could have beneficial effects on quality of life and preservation of the spermatic structures due to a decreased foreign-body reaction. A total of 59 male patients planned for primary, unilateral or bilateral inguinal hernia repair were randomized between a standard polypropylene (Marlex) or lightweight mesh (Vypro II, TiMesh). Main outcome measures were fertility aspects, assessed preoperatively and at 1-year follow-up by semen analysis and scrotal ultrasonography. Secondary outcomes were quality of life (SF-36 and McGill Pain Questionnaire) and recurrence up to 1 year postoperatively. Patients operated on with a VyproII or TiMesh mesh exhibited a decreased sperm motility (vs. preoperatively) compared with Marlex patients, respectively -9.5% and -5.5% versus +2% (P = 0.013). When the results after uni- and bilateral hernia repair were analyzed separately, this difference only remained significant in the bilateral hernia subgroup: -10% for VyproII and -17% for TiMesh versus +1% for Marlex (P = 0.037). Other fertility parame...Continue Reading

References

Aug 1, 1989·Pain·R J VerkesJ Van der Meij
Nov 1, 1996·Annals of Surgery·J CunninghamN A Hagen
Jul 15, 1998·Biomaterials·J M BellónA Carrera-San Martín
Dec 22, 2000·Spine·J E Ware
Jan 17, 2002·The New England Journal of Medicine·D S GuzickUNKNOWN National Cooperative Reproductive Medicine Network
Jul 23, 2002·BJU International·P F RidgwayA W Darzi
Jan 7, 2003·The Clinical Journal of Pain·Amudha S PoobalanW Alastair Chambers
Mar 5, 2003·Radiology·Vikram S DograDeborah J Rubens
Sep 11, 2004·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·H ScheidbachF Köckerling
Sep 11, 2004·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·F H BerndsenA Montgomery
Dec 22, 2004·American Journal of Surgery·Samir S Awad, Shawn P Fagan
Dec 20, 2005·Hernia : the Journal of Hernias and Abdominal Wall Surgery·Christian PeiperVolker Schumpelick
Apr 4, 2006·Hernia : the Journal of Hernias and Abdominal Wall Surgery·W SzczesnyS Dabrowiecki
Jun 14, 2006·Hernia : the Journal of Hernias and Abdominal Wall Surgery·Z MalazgirtM Ertem
Nov 2, 2006·World Journal of Urology·Harry FischErik T Goluboff
Mar 14, 2007·Hernia : the Journal of Hernias and Abdominal Wall Surgery·M MiserezJ B Flament

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Citations

Feb 9, 2012·Surgical Endoscopy·Andrew CurrieSanjay Taribagil
Jan 18, 2014·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·U Klinge, D Weyhe
Feb 15, 2014·Applied Health Economics and Health Policy·Dmitrij Achelrod, Tom Stargardt
Dec 28, 2012·Hernia : the Journal of Hernias and Abdominal Wall Surgery·E PeetersM Miserez
May 28, 2013·Surgical Endoscopy·M M PoelmanH J Bonjer
Dec 29, 2013·Hernia : the Journal of Hernias and Abdominal Wall Surgery·C G Pereira-lucenaM M Linhares
Nov 21, 2013·Hernia : the Journal of Hernias and Abdominal Wall Surgery·F Köckerling, C Schug-Pass
Aug 13, 2014·Hernia : the Journal of Hernias and Abdominal Wall Surgery·A BhanguJ M Blazeby
Aug 31, 2017·Hernia : the Journal of Hernias and Abdominal Wall Surgery·M M RoosJ P J Burgmans
Jul 14, 2017·Annals of Surgery·Andreas Pagh KohlJacob Rosenberg
Jan 14, 2018·Hernia : the Journal of Hernias and Abdominal Wall Surgery·UNKNOWN HerniaSurge Group
May 8, 2019·Hernia : the Journal of Hernias and Abdominal Wall Surgery·F Köckerling
Dec 6, 2016·Hernia : the Journal of Hernias and Abdominal Wall Surgery·E H H MommersT S de Vries Reilingh

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