Laparoscopic multivisceral resection for locally advanced colon cancer: a single-center analysis of short- and long-term outcomes

Surgery Today
Toshiki MukaiMasashi Ueno

Abstract

We evaluated the technical and oncological safety of laparoscopic multivisceral resection (MVR) in selected patients with locally advanced colon cancer (LACC). We compared the clinical backgrounds, and short- and long-term outcomes of patients who underwent laparoscopic vs. those who underwent open MVR for LACC en bloc at our hospital. Between January, 2004 and December, 2015, 140 patients underwent MVR of the primary tumor en bloc via laparoscopic surgery (laparoscopic group; LG, n = 69) or open surgery (open group; OG, n = 71). Laparoscopic surgery was selected mainly for tumors that invaded the bladder and abdominal wall. The LG patients had smaller tumors (60 vs. 80 mm, p < 0.001), less blood loss (30 vs. 181 g, p < 0.001), and shorter hospital stays (12 vs. 19 days, p < 0.001) than the OG patients. Open conversion was required for two patients. Postoperative complications and R0 resection were comparable between the groups. Local recurrence occurred in two LG patients and two OG patients. The 5-year cancer-specific survival, disease-free survival, and local disease-free survival of patients with pT4b disease were not significantly different between the LG and OG groups (90.3% vs. 75.2%, 71.2% vs. 67.6%, and 97.1% vs. 94.2%...Continue Reading

References

May 14, 2004·The New England Journal of Medicine·UNKNOWN Clinical Outcomes of Surgical Therapy Study GroupDavid Ota
Jul 20, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David G JayneUNKNOWN UK MRC CLASICC Trial Group
Dec 25, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Y LiangJ Yu
Nov 18, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Takashi AkiyoshiTetsuichiro Muto
Mar 26, 2009·Surgical Endoscopy·Chunkang YangDana R Sands
Jul 21, 2009·Diseases of the Colon and Rectum·Roland S CronerJonas Goehl
Aug 1, 2005·Clinics in Colon and Rectal Surgery·Ron G Landmann, Martin R Weiser
Dec 15, 2012·Surgical Endoscopy·Marc ZereyUNKNOWN Members of the SAGES Guidelines Committee
Feb 13, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A VignaliC Staudacher
May 9, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yasutomo NagasueToshiharu Yamaguchi
Nov 23, 2013·The British Journal of Surgery·E AytacR P Kiran
Apr 15, 2014·Annals of Surgical Oncology·Vitaliy PoylinDeborah Nagle
Aug 26, 2016·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Yoon Bin JungKang Young Lee
Sep 16, 2016·International Journal of Colorectal Disease·Nicola de'AngelisFrédéric Ris
Oct 13, 2016·World Journal of Gastroenterology : WJG·Marco E AllaixMario Morino
Nov 25, 2016·International Journal of Colorectal Disease·Jeonghyun KangSeung-Kook Sohn
Jan 27, 2017·Asian Journal of Endoscopic Surgery·Ryo TakahashiYoshiharu Sakai
Apr 23, 2017·Surgical Endoscopy·Charlotte E L KlaverPieter J Tanis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.