PMID: 7536266May 1, 1995Paper

Laparoscopic pelvic lymph node dissection combined with real-time interactive transrectal ultrasound guided transperineal radioactive seed implantation of the prostate

The Journal of Urology
Nelson N StoneG Klein

Abstract

Laparoscopic pelvic lymph node dissection with real-time interactive transrectal ultrasound guided transperineal radioactive seed implantation is a new method of treatment for localized carcinoma of the prostate. A total of 58 patients with clinically confined prostate cancer and negative seminal vesicle biopsies underwent staging laparoscopic pelvic lymph node dissection immediately followed by prostate implantation: 50 had 125iodine and 8 had 103palladium implants. Mean operating time was 226 minutes (range 120 to 475), mean blood loss was 57 cc (range 5 to 400) and average hospital stay was 2.2 days (range 0.5 to 8). At a mean followup of 12 months (range 6 to 24), complications included proctitis in 1.7% of the cases, dysuria in 24%, nocturia in 21% and outlet obstruction in 17%. Erectile function remained unchanged. Prostate volume decreased to 58.9% of the pretreatment value by 12 months and to 44.3% by 24 months. Mean prostate specific antigen level was 18.4 +/- 26.3 ng./ml. before treatment, 3.4 +/- 3.9 ng./ml. at 6 months, 2.3 +/- 2.3 ng./ml. at 12 months and 4.9 +/- 6.0 ng./ml. at 24 months (1.2 +/- 1.0 ng./ml. for patients with no evidence of disease). Of the patients 15.8% had local failure at 18 to 24 months as det...Continue Reading

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Citations

Jun 27, 2002·Current Urology Reports·Nelson N Stone, Richard G Stock
Jun 21, 2002·European Urology·N N Stone, R G Stock
Sep 7, 2000·International Journal of Radiation Oncology, Biology, Physics·R M GewanterR D Ennis
Oct 6, 2000·International Journal of Radiation Oncology, Biology, Physics·R G StockJ K DeWyngaert
Dec 1, 2001·International Journal of Radiation Oncology, Biology, Physics·S NagUNKNOWN Clinical Research Committe, American Brachytherapy Society
Mar 2, 2002·International Journal of Radiation Oncology, Biology, Physics·Lucille N LeeNelson N Stone
Feb 19, 2002·International Journal of Radiation Oncology, Biology, Physics·Luca IncrocciPeter C Levendag
May 29, 1999·International Journal of Radiation Oncology, Biology, Physics·F A ViciniA Martinez
Mar 22, 2000·International Journal of Radiation Oncology, Biology, Physics·N N Stone, R G Stock
Apr 20, 2004·Brachytherapy·Nelson N StoneRichard G Stock
Mar 1, 1996·International Journal of Urology : Official Journal of the Japanese Urological Association·T MatsudaO Yoshida
Feb 9, 2010·International Journal of Radiation Oncology, Biology, Physics·Ryan J BurriRichard G Stock
Aug 5, 1999·Hematology/oncology Clinics of North America·R G Stock, N N Stone
May 9, 2003·The Urologic Clinics of North America·Nelson N Stone, Richard G Stock
Nov 18, 2003·BJU International·T M de Reijke, M Pilar Laguna
Jun 28, 2012·BJU International·Kurt M SnyderNelson N Stone
Dec 6, 2011·International Journal of Radiation Oncology, Biology, Physics·Kevin ForsytheRichard G Stock
Jul 8, 2011·The Cochrane Database of Systematic Reviews·Frank PeinemannStefan Sauerland
May 10, 2006·Prostate Cancer and Prostatic Diseases·P L AcherR P Beaney

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