Laparoscopic radical prostatectomy: minimum 3-year follow-up of the first 100 patients in the UK

BJU International
Christopher G Eden, Daniel A Moon

Abstract

To present the results of the first 100 patients in the UK treated by laparoscopic radical prostatectomy (LRP) and with at least 3 years of follow-up, as LRP continues to develop as a minimally invasive alternative to open radical prostatectomy. In all, 100 patients (mean age 62 years, range 52-72) had a transperitoneal LRP by one surgeon during a 25-month period from 2000 to 2002. Most (78%) patients had a prostate-specific antigen level of 4-10 ng/mL, clinical stage T1 disease (62%), and Gleason 6 on biopsy (50%). Sixty-four patients had unilateral or bilateral nerve preservation and 14 had pelvic lymphadenectomy. The mean operative duration was 245 min, with a 1% conversion rate. Three patients received a blood transfusion and three had major complications, including a rectal injury. The positive margin rate was 16% and correlated with pathological variables. At > or = 3 years of follow-up (mean 3.7) the overall survival rate was 99% and the biochemical progression-free survival was 88% in all patients, at 90% for pT2 and 75% for pT3. Ninety patients used 0-1 pads/day (84% pad-free) and 60 undergoing nerve preservation retained erectile function. This series includes the first results for LRP with a > or = 3-year follow-up r...Continue Reading

References

May 11, 1999·JAMA : the Journal of the American Medical Association·C R PoundP C Walsh
Aug 5, 2000·Current Opinion in Urology·G Janetschek, M Marberger
Jan 17, 2002·The Journal of Urology·Gerald W HullPeter T Scardino
Oct 19, 2002·Urology·Gaëalle FromontGuy Vallancien
Dec 4, 2002·BJU International·C G EdenM I Dauleh
Apr 11, 2003·The Journal of Urology·Jens RassweilerThomas Frede
May 17, 2005·BJU International·Andreas LunacekHannes Strasser
Aug 12, 2005·The Journal of Urology·François RozetGuy Vallancien
Sep 8, 2005·The Journal of Urology·Jens-Uwe StolzenburgMichael C Truss

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Citations

Aug 28, 2007·Current Treatment Options in Oncology·Kevin C ZornArieh L Shalhav
Apr 19, 2007·Prostate Cancer and Prostatic Diseases·M ManoharanM S Soloway
May 6, 2008·Urology·David S Yee, David K Ornstein
Apr 11, 2008·Urology·G O Hellawell, D A Moon
Apr 11, 2008·Urology·Andrew J RichardsChristopher G Eden
Apr 11, 2007·BJU International·Benjamin E AyresRaj A Persad
Sep 26, 2007·Expert Review of Anticancer Therapy·Vipul R PatelGeoff Coughlin

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