PMID: 15368924Sep 17, 2004Paper

Laparoscopic surgery for renal cancers

Bulletin de l'Académie nationale de médecine
Guy VallancienFrançois Rozet

Abstract

327 patients with renal adenocarcinoma underwent laparoscopic radical nephrectomy (n=123), radical open nephrectomy (n=113), laparoscopic partialnephrectomy (n=47) or partial open nephrectomy (n=20) for stage T1 disease. Eighteen patients underwent open radical nephrectomy and six laparoscopic radical nephrectomy for stage T2 and T3 disease. Median tumor size was 9.6 cm after open surgery and 4.1 cm after laparoscopic surgery (p<0.01). Intraoperative blood loss was 254 ml during laparoscopy and 460 ml during open surgery (p<0.01). The hospital stay lasted 4.5 days after laparoscopic surgery and 10 days after open surgery (p<0.01). Complications were the same in the two groups, affecting 21.5 and 27.5% of patients, respectively (NS). Oncological results: stage for stage, the results were identical in the open and laparoscopic groups. The specific actuarial recurrence-free survival rate at 5 years among patients with stage PT1 disease was 97% after open radical nephrectomy and 96.8% after laparoscopic surgery; the corresponding rates were 100% after partial open surgery and 100% after laparoscopic partial surgery. Thus, laparoscopic surgery for renal adenocarcinoma offers identical oncological results to open surgery for patients...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.