Laparoscopic treatment of polycystic ovaries: is its place diminishing?

Current Opinion in Obstetrics & Gynecology
Raedah Al-Fadhli, T Tulandi

Abstract

The purpose of this review is to provide a critical discussion on the place of laparoscopic ovarian drilling and medical treatment with metformin for polycystic ovary syndrome. Laparoscopic ovarian drilling remains popular. It is associated with an ovulation rate of approximately 80% and a pregnancy rate of 50-60% within 1 year of the procedure. The technique results in a decrease in ovarian stromal blood flow. An increasing amount of data, however, suggests that treatment with metformin is equally as effective. The use of metformin in pregnancy appears to be safe; it decreases the miscarriage rate and possibly the incidence of gestational diabetes. Laparoscopic ovarian drilling and metformin improve ovulatory dysfunction and pregnancy rate to a similar extent. The advantages of metformin continue beyond conception. It reduces the miscarriage rate and also decreases the likelihood of developing gestational diabetes. A randomized trial comparing the effects of metformin and laparoscopic ovarian drilling in women with polycystic ovary syndrome is recommended.

References

Jan 1, 1976·American Journal of Obstetrics and Gynecology·R ToaffM R Peyser
Aug 1, 1994·Fertility and Sterility·T Gürgan, B Urman
Sep 20, 2001·Archives of Gynecology and Obstetrics·C Batukan, B Baysal
Feb 12, 2002·The Journal of Clinical Endocrinology and Metabolism·Richard FlemingNaveed Sattar
Oct 31, 2002·Human Reproduction·Charles J GlueckLuann Sieve-Smith
Feb 21, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Mulazim YildirimHaldun Guner
May 17, 2003·Fertility and Sterility·Antoni J DulebaLeszek Pawelczyk
May 29, 2003·Gynécologie, obstétrique & fertilité·H FernandezJ Kadoch
Jul 2, 2003·Human Reproduction·Mohammad Ebrahim ParsanezhadErnst Heinrich Schmidt
Aug 12, 2003·Fertility and Sterility·Imran Pirwany, Togas Tulandi
Feb 18, 2004·Fertility and Sterility·Gustavo Arantes Rosa MacielEdmund C Baracat

❮ Previous
Next ❯

Citations

Oct 1, 2005·Archives of Gynecology and Obstetrics·Nikiforos BallianGregory A Kaltsas
Feb 23, 2011·International Journal of Women's Health·Ahmed Badawy, Abubaker Elnashar
Apr 11, 2018·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Nasser KamalAbd-Elbar Sharaf
Jun 21, 2006·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Stefano PalombaFulvio Zullo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.