PMID: 11314942Apr 21, 2001Paper

Laparoscopy predicts metastatic disease and spares laparotomy in selected patients with pancreatic nonfunctioning islet cell tumors

Annals of Surgical Oncology
S N HochwaldK C Conlon

Abstract

Our objective was to compare the efficacy of CT alone to CT followed by laparoscopy in determining resectability of pancreatic nonfunctioning islet (NFI) cell tumors. A retrospective analysis from 1993 to 1999 revealed 48 patients who underwent surgical evaluation for NFI cell tumors. Of these, 34 (71%) patients underwent laparoscopy and CT for either diagnostic purposes or tumor staging. CT and laparoscopic criteria for curative resectability were defined and the sensitivity, specificity, and predictive value of both modalities in determining resectability were calculated. The most frequent tumor location and presenting symptoms were pancreatic head (n = 27, 56%) and abdominal pain (n = 31, 65%), respectively. Median tumor size was 4.0 cm. In the laparoscopy group, curative resection was performed in 20 cases (59%). CT followed by laparoscopy was more sensitive than CT alone in predicting resectability (93% vs. 50%, P = 0.03) with similar specificity (both 100%). The predictive value for tumor resectability was 74% for CT alone and 95% for CT followed by laparoscopy. Reasons for unresectability identified at laparoscopy but not indicated by CT were liver metastases (n = 6) or nodal disease (n = 1). Four of these patients were ...Continue Reading

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Citations

Jul 12, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Swee H TehBrett C Sheppard
May 13, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·C K EnestvedtK G Billingsley
Mar 14, 2009·Current Gastroenterology Reports·Karen Davies, Kevin C Conlon
Sep 22, 2007·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Kwong-Kwok WongDavid M Gershenson
Apr 7, 2010·The Surgical Clinics of North America·David A Kooby, Carrie K Chu
Feb 4, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D D YouD W Choi
Mar 1, 2008·Journal of the American College of Surgeons·Rebekah WhitePeter Allen
Oct 11, 2002·Annals of Surgical Oncology·Kevin C Conlon, Ross L McMahon
Nov 2, 2007·Journal of the American College of Surgeons·Keith D Lillemoe, Jay L Grosfeld

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