Large gangliocytic paraganglioma of the duodenum: A rare entity

World Journal of Gastrointestinal Surgery
Alejandra Gordillo HernándezFernando Oliva Mompean

Abstract

Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence.

Citations

Sep 1, 2016·Case Reports in Gastrointestinal Medicine·Masaya IwamuroHiroyuki Okada
Sep 23, 2016·Annals of Medicine and Surgery·Mina GuergesMalik McKany
Dec 20, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ching-Shu ChiangShin-E Wang
Jan 18, 2017·Gastroenterology Research and Practice·Yoichiro OkuboYoichi Kameda

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