PMID: 3711381May 1, 1986

Large keratoacanthomas in difficult locations treated with intralesional 5-fluorouracil

Journal of the American Academy of Dermatology
C M Parker, C W Hanke

Abstract

Keratoacanthoma is a benign tumor; however, it may cause massive destruction of normal tissue during its rapid growth phase. Intralesional 5-fluorouracil (5-FU) has been shown to be an effective treatment for keratoacanthoma. We have successfully treated five patients with large keratoacanthomas in difficult locations. There have been no recurrences during follow-up periods ranging from 18 to 45 months. Intralesional 5-FU may be ineffective for keratoacanthomas that are not rapidly proliferating.

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Citations

Nov 2, 2002·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Scott SandersKishwer S Nehal
Dec 4, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Lisa G MorseEdward Parry
Aug 7, 2013·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Katelyn ChitwoodGeorge Cohen
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Mar 14, 2019·Dermatologic Therapy·Norbert KissNorbert Wikonkál
Oct 9, 2019·Journal of Cutaneous Medicine and Surgery·Edward W SegerTing Wang
Jun 21, 2012·Journal of Cutaneous Medicine and Surgery·Nicolas AubutJoël Claveau

Related Concepts

Favre-Racouchot Syndrome
5-FU medac
Injectables
Keratoacanthoma

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