Large PAMAM Dendron Induces Formation of Unusual P43 32 Mesophase in Monoolein/Water Systems

Langmuir : the ACS Journal of Surfaces and Colloids
Manoj KumarGuruswamy Kumaraswamy

Abstract

Compact macromolecular dendrons have previously been shown to induce the formation of discontinuous inverse micellar assemblies with Fd3 m symmetry in monoolein/water systems. Here, we demonstrate that a large PAMAM dendron (G5: fifth generation) induces the formation of a very unusual mesophase with P4332 symmetry. This mesophase had previously been observed in monoolein/water systems only on addition of cytochrome c. The P4332 mesophase can be considered an intermediate phase between the bicontinuous Ia3 d and discontinuous micellar mesophases. We present a detailed investigation of the phase behavior of monoolein/water as a function of G5 concentration and temperature. Addition of 1% G5 in 85/15 monoolein/water system induces a transition from the Lα to Ia3 d phase. Further increase in G5 concentration to above 2% induces the formation of the P4332 phase. In contrast to this, incorporation of lower generation PAMAM dendrons (G2-G4) in monoolein/water yields a qualitatively different phase diagram with the formation of the reverse micellar Fd3 m phase. PAMAM dendrons of all generations, G2-G5, bear terminal amine groups that interact with the monoolein headgroup. The compact molecular architecture of the dendrons and these at...Continue Reading

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Oct 30, 2021·Chemistry : a European Journal·Evgeny Apartsin, Anne-Marie Caminade

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