Large-scale flexible metal-covered polymer nanopillar arrays as highly uniform and reproducible SERS substrates for trace analysis

Nanotechnology
Jing WuChaonan Wang

Abstract

While surface-enhanced Raman scattering (SERS) spectroscopy has been studied extensively due to its sensitivity to molecular vibration states, the fabrication of SERS substrates with homogeneous activity over a large area still remains difficult. Here, a facial fabrication of large-scale metal-covered polymer nanopillar arrays used as reliable SERS substrates was developed by nano-pouring process using porous alumina membranes. Our strategy integrates the advantages of low-cost production, high reproducibility and good biocompatibility because the flexible transparent polymer nanopillars are nondestructive to biomaterial surfaces. The as-prepared SERS substrates exhibit highly uniform Raman signals with low relative standard deviation values of 4% at 1169 cm-1 of CV and 8.1% at 1355 cm-1 of R6G, both with the concentration of 10-5 M. The results also show that more than 95% intensity within the limits of the ±10% deviation of the average intensity of signals, indicating excellent stability of SERS signals. In addition, the mechanically flexible substrates can be attached to surfaces with complex morphologies and the good transparency makes the excitation and collection of signals from the backside of the substrates possible, sh...Continue Reading

References

Aug 5, 1996·Physical Review Letters·F J García-Vidal, J B Pendry
Nov 23, 2000·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·H XuP Apell
Jun 18, 2002·Science·M SteinhartU Gösele
Feb 16, 2006·Journal of the American Chemical Society·Seung Joon LeeMartin Moskovits
Apr 30, 2008·Chemical Society Reviews·Janina KneippKatrin Kneipp
Feb 17, 2011·Analytical Chemistry·Stefan A MeyerPablo G Etchegoin
Aug 11, 2011·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Kwan Kim, Kuan Soo Shin
Oct 9, 2012·Physical Chemistry Chemical Physics : PCCP·Samuel L KleinmanRichard P Van Duyne
Jan 23, 2014·Nano Letters·Alexander J WhiteMichael Galperin
Jan 1, 2016·Proceedings of the National Academy of Sciences of the United States of America·Shikuan YangTak-Sing Wong
Nov 29, 2016·Nature Nanotechnology·Liaoyong WenYong Lei
Sep 28, 2017·ACS Applied Materials & Interfaces·Qi HaoOliver G Schmidt
Nov 5, 2017·Nature Communications·Shikuan YangTak-Sing Wong
Nov 14, 2017·Journal of the American Chemical Society·Swati TanwarTapasi Sen

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