Feb 17, 2014

Large-scale non-targeted metabolomic profiling in three human population-based studies

BioRxiv : the Preprint Server for Biology
Andrea GannaErik Ingelsson

Abstract

Non-targeted metabolomic profiling is used to simultaneously assess a large part of the metabolome in a biological sample. Here, we describe the dataset of a large UPLC-Q-TOFMS-based metabolomic profiling effort using plasma and serum samples from participants in three Swedish population-based studies of middle-aged and older human subjects: TwinGene, ULSAM and PIVUS, including more than 3,600 participants in total. At present, more than 200 metabolites have been manually annotated in the three cohorts using an in-house library of standards and publically available spectral databases. Data available at the Metabolights repository include individual raw unprocessed data, processed data, basic demographic variables and spectra of annotated metabolites. Additional phenotypical and genetic data is available upon request to cohort steering committees.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Metabolic Process, Cellular
Study
Participant
Plasma
cDNA Library
Metabolite
Metabolomics
Steering Committee
Cohort
Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.