Large symptomatic pericardial effusion as the presentation of unrecognized cancer: a study in 173 consecutive patients undergoing pericardiocentesis

Medicine
Shomron Ben-HorinA Livneh

Abstract

Large symptomatic pericardial effusion (PE)-PE that causes hemodynamic compromise-can be the initial presentation of an unrecognized underlying malignancy. However, the prevalence and features of this association have not been thoroughly characterized. We performed a retrospective study of all patients with hemodynamically significant PE who underwent pericardiocentesis in a 9-year period (1995-2004) in a tertiary hospital. Etiologies of pericardial disease were diagnosed using predetermined criteria. Demographic and clinical data of patients with hemodynamically significant PE as the presentation of their malignant disease were compared to those with established neoplastic disease, and to those with other etiologies. We identified 173 patients who underwent pericardiocentesis during the study period. Neoplastic PE was found in 58 patients (33%), 45 of whom had a known malignant disease at the time of pericardiocentesis. Pericardial disease was found to be the presentation of an unrecognized underlying neoplastic disease, mostly a lung tumor, in 13 patients (7.5% of all etiologies). After exclusion of pericardial effusions with easily attributable causes by clinical circumstances, physical examination, and simple laboratory tes...Continue Reading

References

Feb 13, 1975·The New England Journal of Medicine·A Bohan, J B Peter
Jun 1, 1988·Clinical Cardiology·A ColomboJ M Gardin
Oct 1, 1985·The American Journal of Cardiology·G Permanyer-MiraldaJ Soler-Soler
Nov 1, 1982·Arthritis and Rheumatism·E M TanR J Winchester
Aug 1, 1993·The American Journal of Medicine·G R CoreyT C Wall
Feb 1, 1993·The American Journal of the Medical Sciences·R M Fincher
May 1, 1997·Chest·D G MeyersT W Prendergast
Oct 23, 1997·Arthritis and Rheumatism·A LivnehM Pras
Aug 4, 1998·International Journal of Cardiology·N Islam, M Y Ahmedani
Sep 1, 2000·The American Journal of Medicine·J Sagristà-SauledaJ Soler-Soler
Feb 9, 2002·Chest·Lesley J BurgessAnton F Doubell
Dec 10, 2003·Medicine·Pierre-Yves LevyDidier Raoult

❮ Previous
Next ❯

Citations

Aug 4, 2007·Pediatric Cardiology·B KühnR E Breitbart
Mar 4, 2015·International Journal of Cardiology·Frederick M Howard, Akshar Y Patel
Jan 1, 2016·The American Journal of Cardiology·Cristina Sánchez-EnriqueAntonio Fernández-Ortiz
Sep 10, 2013·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Luís Ferreira dos SantosOliveira Santos
Feb 1, 2012·Current Problems in Cardiology·David M DudzinskiJudy W Hung
Mar 1, 2011·Annals of Emergency Medicine·Murdoch Leeies, Erin Weldon
Dec 30, 2015·American Journal of Clinical Pathology·Lisa M RooperMatthew T Olson
Jul 4, 2007·The American Journal of Emergency Medicine·Pierluigi BallardiniRoberto Manfredini
Mar 27, 2012·The American Journal of Medicine·Christopher Sankey
Nov 14, 2014·Revue des maladies respiratoires·G Rousseau-BussacC Chouaid
May 11, 2016·BMC Pulmonary Medicine·Kenichi OkudaTakahide Nagase
Jun 12, 2016·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Navin R MahadevanRichard N Mitchell
May 5, 2007·The American Journal of Cardiology·Shomron Ben-HorinAvi Livneh
Jul 27, 2018·JAAPA : Official Journal of the American Academy of Physician Assistants·Shalon R Buchs, Jessica N Perry
Dec 25, 2017·Journal of the American Heart Association·Alexander StrobbePeter R Sinnaeve
Jan 17, 2020·JAMA Oncology·Alexia ChristinMichel Obeid
May 29, 2012·Heart Failure Reviews·Konstantinos KaratoliosBernhard Maisch
Apr 13, 2021·Curēus·Lalitha Padmanabha VemireddyMaryna Shayuk
May 11, 2021·Frontiers in Cardiovascular Medicine·Nathaniel R WilsonCezar A Iliescu
Jun 12, 2021·Curēus·Andrii MaryniakYi-Chun Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The American Journal of Medicine
J Sagristá-SauledaJ Soler-Soler
The American Journal of Medicine
G R CoreyT C Wall
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
F M González ValverdeJ L Vázquez
© 2021 Meta ULC. All rights reserved