Larvicidal activity of Zanthoxylum acanthopodium essential oil against the malaria mosquitoes, Anopheles anthropophagus and Anopheles sinensis

Malaria Journal
Qi HeLiang Zhu

Abstract

Zanthoxylum acanthopodium has insecticidal effect in Chinese traditional medicine. In this study, the essential oil from the dried Zanthoxylum plant was used as a larvicidal compound against the malaria mosquitoes, Anopheles anthropophagus and Anopheles sinensis. Compounds in the Zanthoxylum essential oil were investigated by gas chromatography and mass spectroscopy (GC-MS). The larvicidal bioassays of the whole oil, as well as the main compounds in the oil (estragole and eucalyptol) were performed using WHO method. In total, 63 main compounds (99.32%) were found in the oils, including estragole (15.46%), eucalyptol (10.94%), β-caryophyllene (5.52%), cis-linalool oxide (3.76%), cis-limonene oxide (3.06%). A dose-dependent effect on mortality was recorded with increasing concentrations of essential oil and compounds increasing mortality of the larvae. Larvicidal bioassays revealed that 24 h LC50 of the whole essential oil was 36.00 mg/L and LC90 was 101.49 mg/L against An. anthropophagus, while LC50 was 49.02 mg/L and LC90 was 125.18 mg/L against An. sinensis. Additionally, 24 h LC50 of estragole were 38.56 and 41.67 mg/L against An. anthropophagus and An. sinensis, respectively, while the related LC90 were 95.90 and 107.89 mg/L...Continue Reading

References

Feb 8, 2002·Nature·Louis H MillerOgobara K Doumbo
Feb 8, 2002·Nature·Jeffrey Sachs, Pia Malaney
Apr 9, 2002·The Lancet Infectious Diseases·Chansuda WongsrichanalaiSteven R Meshnick
Oct 5, 2002·Science·Robert A HoltStephen L Hoffman
May 17, 2005·Journal of Ethnopharmacology·Alex AsaseMonique S J Simmonds
Jul 26, 2005·Phytotherapy Research : PTR·Yuwadee TrongtokitChamnarn Apiwathnasorn
Aug 16, 2005·Trends in Parasitology·Jean-Paul AnthonyHuw Smith
Sep 29, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·David J Weber, William A Rutala
Aug 7, 2009·Medical Hypotheses·Steven Lehrer
Apr 15, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Cheng Fang WangLigang Zhou
Apr 10, 2013·Asian Pacific Journal of Tropical Biomedicine·Somia El-MaghrabyOmnia M H M Kamel
Apr 19, 2015·Malaria Journal·James E GentileGregory R Madey

❮ Previous
Next ❯

Citations

Dec 11, 2019·Biomolecules·Diogo Vilar da FonsêcaDamião Pergentino de Sousa
Jun 25, 2021·Journal of Ethnopharmacology·Xiaohan WeiXiaomei Tan

❮ Previous
Next ❯

Software Mentioned

Statistical Package of Social Sciences ( SPSS )

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.