Larvicidal and Biting Deterrent Activity of Essential Oils of Curcuma longa, Ar-turmerone, and Curcuminoids Against Aedes aegypti and Anopheles quadrimaculatus (Culicidae: Diptera)

Journal of Medical Entomology
Abbas AliIkhlas Khan

Abstract

Essential oils and extract of Curcuma longa, ar-turmerone, and curcuminoids were evaluated for their larvicidal and deterrent activity against mosquitoes. Ar-turmerone and curcuminoids constituted 36.9, 24.9 and 50.6% of rhizome oil, leaf oil, and rhizome extract, respectively. Ar-turmerone was the major compound of the rhizome oil (36.9%) and leaf oil (24.9%). The ethanolic extract had 15.4% ar-turmerone with 6.6% bisdesmethoxycurcumin, 6.1% desmethoxycurcumin, and 22.6% curcumin. In in vitro studies, essential oils of the leaf (biting deterrence index [BDI] = 0.98), rhizome (BDI = 0.98), and rhizome ethanolic extract (BDI = 0.96) at 10 µg/cm(2) showed biting deterrent activity similar to DEET at 25 nmol/cm(2) against Aedes aegypti L. Among the pure compounds, ar-turmerone (BDI = 1.15) showed the biting deterrent activity higher than DEET at 25 nmol/cm(2) whereas the activity of other compounds was lower than DEET. In Anopheles quadrimaculatus Say, only ar-turmerone showed deterrent activity similar to DEET. In dose-response bioassay, ar-turmerone showed significantly higher biting deterrence than DEET at all the dosages. Ar-turmerone, at 15 nmol/cm(2), showed activity similar to DEET at 25 nmol/cm(2) and activity at 5 nmol/cm...Continue Reading

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Citations

Sep 25, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Olivier Gnankiné, Imaël Henri Nestor Bassolé
Nov 22, 2017·Biomédica : revista del Instituto Nacional de Salud·Sergio Andrade OchoaBenjamín Nogueda-Torres
Feb 1, 2020·Pest Management Science·Abbas AliIkhlas A Khan
May 21, 2020·Environmental Science and Pollution Research International·Francine Perri VenturiniVanderlei Salvador Bagnato
Apr 1, 2019·Veterinary World·Sobhy Abdel-ShafyMohammad Yahya Alshahrani
Dec 11, 2019·Biomolecules·Diogo Vilar da FonsêcaDamião Pergentino de Sousa

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