Abstract
Essential oils and extract of Curcuma longa, ar-turmerone, and curcuminoids were evaluated for their larvicidal and deterrent activity against mosquitoes. Ar-turmerone and curcuminoids constituted 36.9, 24.9 and 50.6% of rhizome oil, leaf oil, and rhizome extract, respectively. Ar-turmerone was the major compound of the rhizome oil (36.9%) and leaf oil (24.9%). The ethanolic extract had 15.4% ar-turmerone with 6.6% bisdesmethoxycurcumin, 6.1% desmethoxycurcumin, and 22.6% curcumin. In in vitro studies, essential oils of the leaf (biting deterrence index [BDI] = 0.98), rhizome (BDI = 0.98), and rhizome ethanolic extract (BDI = 0.96) at 10 µg/cm(2) showed biting deterrent activity similar to DEET at 25 nmol/cm(2) against Aedes aegypti L. Among the pure compounds, ar-turmerone (BDI = 1.15) showed the biting deterrent activity higher than DEET at 25 nmol/cm(2) whereas the activity of other compounds was lower than DEET. In Anopheles quadrimaculatus Say, only ar-turmerone showed deterrent activity similar to DEET. In dose-response bioassay, ar-turmerone showed significantly higher biting deterrence than DEET at all the dosages. Ar-turmerone, at 15 nmol/cm(2), showed activity similar to DEET at 25 nmol/cm(2) and activity at 5 nmol/cm...Continue Reading
References
May 19, 1998·Journal of Natural Products·G N RothM G Nair
Aug 18, 2001·Planta medica·A P MartinsJ Casanova
Apr 11, 2002·Journal of Economic Entomology·A K TripathiS Kumar
Mar 6, 2003·Journal of Agricultural and Food Chemistry·Moo-Key KimHoi-Seon Lee
Feb 11, 2005·Chemical Senses·Renate C SmallegangeWillem Takken
Apr 7, 2005·Fitoterapia·Somia KhattakManzoor Ahmad
Apr 9, 2005·Vector Borne and Zoonotic Diseases·Marvin S GodseyNicholas Komar
Apr 14, 2005·Journal of the American Mosquito Control Association·Jerome A KlunMustapha Debboun
Jul 30, 2005·Bioresource Technology·Veena PrajapatiS P S Khanuja
Jun 16, 2007·Advances in Experimental Medicine and Biology·Bharat B AggarwalHaruyo Ichikawa
Apr 29, 2008·Journal of the American Mosquito Control Association·Junwei ZhuRui-De Xue
Apr 9, 2009·Journal of Medical Entomology·Julia W PridgeonKenneth J Linthicum
Jan 1, 2000·Pharmaceutical Biology·C Latha, J Ammini
May 29, 2012·Acta Tropica·M SagnouA Michaelakis
Dec 29, 2012·Journal of Medical Entomology·Abbas AliIkhlas Khan
May 23, 2014·Journal of Medical Entomology·Abbas AliNurhayat Tabanca
Citations
Feb 9, 2017·Journal of Agricultural and Food Chemistry·Juan LiHong-Yi Qi
Mar 28, 2017·Journal of Agricultural and Food Chemistry·Hongyi QiLi Li
Sep 25, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Olivier Gnankiné, Imaël Henri Nestor Bassolé
Nov 22, 2017·Biomédica : revista del Instituto Nacional de Salud·Sergio Andrade OchoaBenjamín Nogueda-Torres
Feb 1, 2020·Pest Management Science·Abbas AliIkhlas A Khan
May 21, 2020·Environmental Science and Pollution Research International·Francine Perri VenturiniVanderlei Salvador Bagnato
Nov 7, 2019·Journal of Medical Entomology·Nael AbutahaMuhammad Farooq
Jun 4, 2020·Insects·Jia LiuGuanghui Dai
Apr 1, 2019·Veterinary World·Sobhy Abdel-ShafyMohammad Yahya Alshahrani
Dec 11, 2019·Biomolecules·Diogo Vilar da FonsêcaDamião Pergentino de Sousa
Jan 21, 2021·Pest Management Science·Natasha Ferreira MezzacappoVanderlei Salvador Bagnato