Laryngeal Schwannoma: A Case Presentation and Review of the Mayo Clinic Experience

Journal of Voice : Official Journal of the Voice Foundation
Jonathan J RomakDale C Ekbom

Abstract

The aim of this study was to clarify the nature of laryngeal schwannomas through review of the experience of a single institution during a 104-year period. This is a retrospective case series. The Mayo Clinic, Rochester, Minnesota clinical and surgical pathology database was reviewed for the years 1985-2011. Four cases of laryngeal schwannoma were identified. These cases were pooled with a previously published series of laryngeal schwannomas treated at our institution between 1907 and 1986. The characteristics of all 11 cases were studied, and relevant literature was reviewed. A total of 11 cases of schwannoma of the larynx were identified. The mean age at presentation was 48 years (range 12-73 years). The most common presenting symptoms were dysphonia and dysphagia. The most frequently involved primary site was the false vocal fold (six patients), followed by the aryepiglottic fold (three), epiglottis (two), subglottis (two), ventricle (one), true vocal fold (one) and postcricoid region (one). The mean maximal tumor diameter was 2.5 cm. In all but one case, surgical excision was curative with no recurrence during recorded follow up ranging from 1 to 17 years. Laryngeal schwannomas, although rare, should be considered in the di...Continue Reading

References

Nov 1, 1987·The Annals of Otology, Rhinology, and Laryngology·R J StanleyH B Neel
Dec 2, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·P Zbären, R Markwalder
Aug 6, 2002·The Laryngoscope·Frederick S RosenFrancis B Quinn
May 25, 2007·Head & Neck·Elisa RognonePaolo Tortori-Donati
Jul 10, 2009·Head & Neck Oncology·Jörg EbmeyerHolger Sudhoff
Aug 25, 2011·Auris, Nasus, Larynx·Rumi Ishida UehaTakaharu Nito
Sep 22, 2012·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Aisha HarunHoward W Francis

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Citations

Oct 19, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michele TulliMario Bussi
May 3, 2019·Breast Disease·Omar HamdyMohammad Hamdy
Jul 1, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ozlem SaraydarogluHakan Coskun
Oct 10, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Andrew C OngMajid A Khan
Aug 6, 2021·Laryngo- rhino- otologie·Stephan HackenbergAgmal Scherzad

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