Laser ablation patterning by interference induces directional cell growth

IEEE Transactions on Nanobioscience
Ping LiClaus-Michael Lehr

Abstract

Laser-patterning by interference is a method to introduce micropatterns on the surface of TXL and TXB, which were shown to have an effect on the L929 growth. In this experiment, we have produced collagen-coated and laser-patterned TXL and TXB with different dimensions; the groove width of the line patterns varied approximately from 1.2 microm to 9.7 microm, ridge depth varied from 0.4 microm to 1.3 microm, and the groove depth varied between 0.4 microm and 1.3 microm. Therefore, a homogeneous smooth surface was achieved, and that L929 growth was only affected by the different dimensions of the line patterns. All the laser-patterned TXL and TXB have shown inducing different degrees of directional growth of L929 that the cells grew in the direction aligning the microgrooves. However, the different widths of the microgrooves were demonstrated to play an important role in determining cell morphology and growth orientation. For example, cells were elongated when they grew on the narrower widths, which were 1.26 microm, 1.91 microm, and 5.04 microm while cells tended to be triangular when grew on wider width about 9.76 microm. In addition, L929 might grow only on the top of the laser-patterns attaching the ridges when the groove widt...Continue Reading

Citations

Sep 14, 2010·Biointerphases·Prafulla ChandraJoachim Kohn
Sep 2, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Bassam Al MeslmaniUdo Bakowsky
Sep 14, 2010·Biomaterials·Kristian KolindFlemming Besenbacher
Aug 12, 2009·Journal of Controlled Release : Official Journal of the Controlled Release Society·Juliane NguyenThomas Kissel
Jan 26, 2010·Biomaterials·Will W MinuthAnne Glashauser
Oct 18, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Erica RoiteroEmilio Jiménez-Piqué
Feb 3, 2007·Journal of Biomedical Materials Research. Part a·Keith R Milner, Christopher A Siedlecki
Jul 25, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Lars IversenDimitrios Stamou
Oct 31, 2017·ACS Applied Materials & Interfaces·Francesca SantoroAlberto Salleo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.