PMID: 9167163May 1, 1997Paper

Laser-based microfocused x-ray source for mammography: feasibility study

Medical Physics
A KrolS C Prasad

Abstract

A laser-produced plasma (LPP) x-ray source with possible application in mammography was created by focusing a laser beam on a Mo target. A Table-Top-Terawatt (TTT) laser operating at 1 J energy per pulse was employed. A dual pulse technique was used. Maximum energy transfer (approximately 10%) from laser light to hot electrons was reached at a 150 ps delay between pulses and the conversion efficiency (hard x-ray yield/laser energy input) was approximately 2 x 10(-4). The created LPP x-ray source is characterized by a very small focal spot size (tens of microns), Gaussian brightness distribution, and a very short pulse duration (a few ps). The spectral distribution of the generated x rays was measured. Images of the focal spot, using a pinhole camera, and images of a resolution pattern and a mammographic phantom were obtained. The LPP focal spot modulation transfer function for different magnification factors was calculated. We have shown that the LPP source in conjunction with a spherically bent, high throughput, crystal monochromator in a fixed-exit Rowland circle configuration can be used to created a narrow band tunable mammography system. Tunability to a specific patient breast tissue thickness and density would allow one t...Continue Reading

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Citations

Jun 1, 2011·Analytical and Bioanalytical Chemistry·Chia-Chi ChienG Margaritondo
Jan 29, 2014·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Z NajmudinM Wing
Jul 31, 1998·Medical Physics·Z JingJ K Walker
May 29, 2009·Medical Physics·Ayhan Bingölbali, C A MacDonald
Feb 7, 2001·Radiology·F ArfelliF Zanconati
Dec 9, 2004·Physics in Medicine and Biology·Theron J HamiltonGerald J Diebold
May 7, 2005·Physics in Medicine and Biology·P BaldelliM Gambaccini
Aug 20, 2010·Radiation Research·Katsutoshi SatoHiroaki Nishimura
Jan 15, 2020·Structural Dynamics·M AfshariK Sokolowski-Tinten
Mar 30, 2001·Physics in Medicine and Biology·C GaudinC Rouillé
Feb 19, 2002·Physics in Medicine and Biology·A OlivoE Castelli
Nov 18, 2020·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Herbert LegallJörg Krüger

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