Laser debulking or tracheotomy in airway management prior to total laryngectomy for T4a laryngeal cancer

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Djamil SemdaiePhilippe Gorphe

Abstract

Retrospective studies have shown that tracheotomy prior to total laryngectomy (TL) is associated with decreased survival. We sought to investigate whether this is due to higher local invasiveness associated with obstructive disease or whether it is the result of tracheotomy itself. We reviewed patients with a T4a (AJCC 7th edition) laryngeal squamous-cell carcinoma treated with a primary TL followed by adjuvant radiotherapy between 2001 and 2013. We compared patients who had obstructive lesions with those who had non-obstructive lesions in terms of preoperative data, pathological features, and treatment outcomes. Second, we compared tracheotomized patients with patients who underwent endoscopic laser debulking (ELD). One hundred patients were reviewed. Thirty-seven of them required an airway intervention prior to a TL (tracheotomy n = 24/ELD n = 13). Patients with obstructive tumors had more frequently subglottic extension (p = 0.0066) and a shorter disease-free survival (DFS) (p = 0.046), due to a higher incidence of additional distant metastases. Tracheotomy was associated with a shorter DFS (p = 0.035) and more frequent perineural invasion (p = 0.0272) as compared to ELD, but not with a higher incidence of stomal recurrence....Continue Reading

References

Dec 1, 1992·American Journal of Surgery·J J ManniG J Hordijk
Feb 1, 1991·Clinical Otolaryngology and Allied Sciences·T J RockleyA P Reid
Jun 1, 1991·The Journal of Laryngology and Otology·A McCombe, P M Stell
Feb 1, 1990·Clinical Otolaryngology and Allied Sciences·M H WickhamP J Bradley
Sep 1, 1987·The Laryngoscope·M S Griebie, G L Adams
Feb 1, 1971·The Journal of Laryngology and Otology·P M Stell, P van den Broek
Jun 1, 1993·The Journal of Laryngology and Otology·F EstebanA Mochon
Jan 1, 1993·American Journal of Otolaryngology·A A NarulaP J Bradley
Feb 1, 2002·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Yutaka ImauchiKeiichi Ichimura
Jan 27, 2005·Head & Neck·Vinidh PaleriMario S Sammut
Mar 25, 2009·American Journal of Clinical Oncology·Houyu ZhaoShixi Liu
Jul 24, 2010·Head & Neck·Jesus E MedinaJochen A Werner
Oct 12, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Thomas F PezierRicard Simo
Apr 20, 2013·Oncology Letters·Sha LiDongwei Gao
Mar 5, 2014·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·A LevyY Tao
Dec 3, 2014·Oral Oncology·Joseph RohSufi M Thomas
Jun 13, 2015·International Journal of Radiation Oncology, Biology, Physics·Surbhi GroverAlexander Lin
Jun 26, 2015·The Laryngoscope·Philippe GorpheStéphane Temam
Aug 25, 2015·European Annals of Otorhinolaryngology, Head and Neck Diseases·D BlanchardUNKNOWN SFORL work-group
Aug 25, 2015·European Annals of Otorhinolaryngology, Head and Neck Diseases·C HalimiUNKNOWN SFORL work-group
Sep 4, 2015·The Laryngoscope·Adriana J TimmermansMichiel W M van den Brekel
Apr 14, 2016·Oncology Letters·Massimo MesolellaFilippo Ricciardiello
Jun 7, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Andrew C BirkelandMatthew E Spector
Jun 10, 2017·Journal of the National Comprehensive Cancer Network : JNCCN·David AdelsteinSusan D Darlow
Aug 19, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marc RemacleFrederik G Dikkers

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Citations

Nov 14, 2019·The New England Journal of Medicine·Antoine EskanderJonathan C Irish
Mar 7, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Hongli GongJian Zhou

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