Laser diffraction studies of sarcomere dynamics during 'isometric' relaxation in isolated muscle fibres of the frog

The Journal of Physiology
K A Edman, F W Flitney

Abstract

1. A study has been made of changes in sarcomere length and tension which occur during relaxation from isometric (;fixed ends') tetani in isolated muscle fibres of the frog. Sarcomere lengths were calculated from measurements of the separation of the zero-to-first-order intensity maxima in diffraction patterns generated by illuminating small segments of fibre with a He-Ne laser. Diffraction spectra were recorded continuously on cine-film using the method of ;streak' photography.2. Many sarcomeres in a muscle fibre are found to undergo active shortening during relaxation, at the expense of others located elsewhere which become passively extended. The time of onset of changes in sarcomere length coincides with the well known ;shoulder' on the tension record, and their amplitude is maximal at the time when isometric force approaches zero. The original pattern of sarcomere lengths is only re-established after tension has disappeared.3. The variability in the pattern of sarcomere length changes during relaxation was studied in a sample of twenty fibres, by making ;streak' recordings from successive 1 mm segments along the entire length of each fibre. This survey showed that segments which elongate are located predominantly, though n...Continue Reading

Citations

Oct 1, 1984·Pflügers Archiv : European journal of physiology·H van den Hooff, T Blangé
Jan 1, 1984·Journal of Mathematical Biology·V ComincioliC Reggiani
Aug 9, 2005·European Journal of Applied Physiology·Naokazu Miyamoto, Shingo Oda
Oct 1, 1994·Acta Physiologica Scandinavica·F Lou, Y B Sun
Oct 24, 1998·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·P ChristovaN Radicheva
Jun 18, 2002·The Journal of Physiology·K A P EdmanB Kronborg
Aug 5, 2009·The Journal of Physiology·E BrunelloM Irving
May 15, 2007·Journal of Biomechanics·C J Barclay, G A Lichtwark
Jan 1, 1990·Journal of Biomechanics·J BobetM N Oğuztöreli
Mar 1, 1984·Acta Physiologica Scandinavica·A Månsson, K A Edman
Apr 1, 1983·Acta Physiologica Scandinavica·A R Khan, K A Edman
Nov 1, 1985·Acta Physiologica Scandinavica·A Månsson, K A Edman
Mar 27, 2010·Biophysical Journal·Gretchen A MeyerRichard L Lieber
Nov 12, 2013·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Emiliano CèFabio Esposito
Aug 6, 1998·IEEE Transactions on Bio-medical Engineering·J Bobet, R B Stein
Aug 1, 1984·Pflügers Archiv : European journal of physiology·R D WoittiezR H Rozendal
Feb 1, 1992·Muscle & Nerve·B R Bigland-RitchieC K Thomas
May 29, 2007·Journal of Muscle Research and Cell Motility·Ivo A Telley, Jachen Denoth
Feb 1, 1990·Pflügers Archiv : European journal of physiology·P J GriffithsC C Ashley
Jan 5, 2005·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·William P S McKayBrian L F Daku
Aug 28, 2009·American Journal of Physiology. Cell Physiology·Ivan PavlovDilson E Rassier
May 23, 2014·The Journal of Biological Chemistry·Francisco AltamiranoJosé R López
Mar 5, 2004·American Journal of Physiology. Cell Physiology·T Radzyukevich, K A P Edman
Nov 21, 2019·European Journal of Applied Physiology·Emiliano CèFabio Esposito
Nov 20, 2016·Journal of Muscle Research and Cell Motility·Alf Månsson
Nov 21, 2019·Journal of Muscle Research and Cell Motility·Giulia VitaleCorrado Poggesi
Feb 1, 1993·Journal of Muscle Research and Cell Motility·R BottinelliC Reggiani
Jun 5, 1998·The American Journal of Physiology·P A WahrJ A Rall
Mar 8, 2005·Pflügers Archiv : European journal of physiology·Corrado PoggesiRobert Stehle
Sep 18, 2017·Journal of Muscle Research and Cell Motility·Robert Stehle, Chiara Tesi
Jun 27, 2018·International Journal of Molecular Sciences·Alf MånssonDilson E Rassier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.