Laser Doppler measurements of the vocal fold blood micro-circulation

Journal of Voice : Official Journal of the Voice Foundation
I StecJ-E Juto

Abstract

The authors have developed a laser Doppler method, referred to as LDF+LS (laser Doppler flowmetry by laryngostereometry), for measuring the vocal fold micro-circulation. The vocal folds of 103 patients were examined during general anesthesia. A laser Doppler probe was placed on defined positions at the vocal fold edge: midmembranous position (MP), 2 mm and 4 mm behind, and 1 mm anterior to MP. Three parameters were derived, ie, the concentration (CMBC) and velocity (V) of moving blood cells, and the product of both resulting in perfusion: P = CMBCxV. The results of 53 subjects with normal vocal fold status showed that the V at MP was significantly lower than 2 mm behind MP (P < 0.05). Men had significantly higher velocity than women (P < 0.05). Subjects older than 65 years had higher perfusion and CMBC as compared with younger subjects (P < 0.01). Smokers with normal vocal folds had higher velocity than non-smokers (P < 0.05). Measurements of healthy vocal folds were compared with benign vocal fold pathology. Vocal fold polyps had significantly higher perfusion than normal vocal folds (P < 0.01). In conclusion, the laser Doppler measurement is a sensitive tool estimating superficial blood flow in both normal and pathological vo...Continue Reading

References

Apr 1, 1987·Archives of Otolaryngology--head & Neck Surgery·K MatsuoT Shin
Jan 1, 1997·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·H Grudemo, J E Juto
Sep 25, 1999·Journal of Voice : Official Journal of the Voice Foundation·J AbitbolB Abitbol
Jul 29, 2003·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·A Jacob, M A Birchall
Nov 1, 2003·The Annals of Otology, Rhinology, and Laryngology·João Aragão Ximenes FilhoLuiz Ubirajara Sennes

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Citations

Nov 7, 2012·The Review of Scientific Instruments·Nie XiaomingLong Xingwu
Jul 21, 2009·Diseases of the Colon and Rectum·Litza E MitalasW Rudolph Schouten

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