PMID: 8594519Feb 1, 1996Paper

Laser suture lysis after mitomycin C trabeculectomy

Ophthalmology
E N MorinelliP P Lee

Abstract

To evaluate the timing, efficacy, and complications of laser suture lysis (LSL) after mitomycin C trabeculectomy in patients with glaucoma at high risk for failure of filtering surgery. The authors retrospectively reviewed the charts of 62 consecutive patients who underwent a total of 66 sessions of LSL after trabeculectomy with mitomycin C. The interval from surgery to LSL ranged from 2 to 65 days (mean +/- standard deviation, 17.9 +/- 14.9 days). The average intraocular pressure (IOP) reduction after LSL was 11.9 +/- 8.9 mmHg (range, 3-40 mmHg). A longer interval to LSL was correlated with a lesser degree of pressure reduction (P=0.0004, Wilcoxon rank-sum test). After LSL, hypotony developed in 13 (21%) patients (IOP < 6 mmHg on 2 consecutive measurements at least 24 hours apart). This resolved spontaneously after 7 to 304 days (104.1 +/- 109.1 days) in 12 (92%) of the 13 patients. Life-table success rates (success defined as 6 mmHg </= final IOP </= 21 mmHg) for the hypotony and no hypotony groups were 100% and 86% (at 6 months) and 96% and 86% (at 12 months), respectively. The final visual acuity worsened in a significantly greater percentage of patients in the hypotony group (46%) compared with the no-hypotony group (18%) ...Continue Reading

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Citations

Oct 3, 2006·Japanese Journal of Ophthalmology·Takeo FukuchiHaruki Abe
Oct 8, 1998·Survey of Ophthalmology·A Azuara-Blanco, L J Katz
May 14, 2010·Clinical Ophthalmology·Takeo FukuchiHaruki Abe
Aug 5, 2003·Journal of Glaucoma·Frederick M Kapetansky
Dec 27, 2005·Journal of Glaucoma·Monica RalliJoseph Caprioli
May 3, 2007·Journal of Glaucoma·Umit AykanAtilla Bayer
Jan 1, 2016·Current Opinion in Ophthalmology·Joseph F PanarelliPaul A Sidoti
Dec 24, 1997·Ophthalmology·D LeeS Y Reed
Sep 16, 2015·Journal of Glaucoma·Michele FigusMarco Nardi
Oct 12, 2014·Journal of Glaucoma·Maria KrömerFlorian Rüfer
Jan 1, 2012·Pharmaceutics·Marcelo L OcchiuttoVital P Costa
Jul 30, 2004·Clinical & Experimental Ophthalmology·Gianmarco ParisWilliam E Sponsel
Oct 4, 2008·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Tarek M Eid
Jan 9, 2016·European Journal of Ophthalmology·Fulya DumanGeorge L Spaeth
Oct 1, 1996·Journal of Clinical Laser Medicine & Surgery

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