Laser therapy of the lung: biophysical background

Der Radiologe
V Knappe, A Mols

Abstract

The laser is a well established surgical instrument in lung therapy. This report provides information on the biophysical basics of the laser-induced thermotherapy (LITT) of lung metastases. Optical properties like absorption and scattering determine the penetration depth of laser radiation in tissue. These parameters vary dynamically during the application and define in combination with thermal tissue properties the achievable destruction volume. Parenchyma behaves very differently compared to more dense tissues due to local inhomogenities and the large amount cavaties filled with air. Beside an account of the affecting parameters an overview of therapy options is given. Therapeutic results depend not only on the tissue properties but also on the technical equipment, e.g. the applicator design and the energy applied. Complex dosimetric models allow for a calculation of the lesion's size in advance.

Citations

Jan 18, 2012·Der Radiologe·C RosenbergN Hosten
Feb 24, 2009·AJR. American Journal of Roentgenology·Christian RosenbergNorbert Hosten
Jan 15, 2014·Journal of Bronchology & Interventional Pulmonology·Murthy R ChamarthyYosef Golowa
Jul 2, 2014·La Radiologia medica·Elena N PetreConstantinos T Sofocleous
Feb 27, 2013·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Helmut SchoellnastStephen B Solomon
Sep 24, 2011·AJR. American Journal of Roentgenology·Constantinos T SofocleousStephen B Solomon

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