Laser treatment of solar lentigines on dorsum of hands: QS Ruby laser versus ablative CO2 fractional laser - a randomized controlled trial

European Journal of Dermatology : EJD
Nicola L SchoenewolfInja Bogdan Allemann

Abstract

Lentigines solares (LS) on the dorsum of hands are often esthetically disturbing. Q-switched ruby laser treatment is highly effective in the treatment of these lesions. Ablative fractional photothermolysis may be a suitable alternative. We compared the Q-switched ruby laser with ablative CO2 fractional photothermolysis for the treatment of solar lentigines. To evaluate the efficacy and side-effects of 694nm Q-switched ruby laser (Sinon) with the ablative 10,600nm CO2 fractional laser (Quantel Excel O2) in an intra-individual side-to-side comparison in the treatment of LS on the dorsum of hands. Eleven patients were included in the study. The hands of each patient were randomized for treatment with the two laser systems. Three treatment sessions were scheduled at weeks 0, 4 and 8. Evaluations by patients, treating physician and blinded experts were scheduled at weeks 0, 4, 8, 16 and 24. The Q-switched ruby laser was significantly more efficacious than the ablative CO2 fractional laser for removing LS on the dorsum of hands (p = 0.01). In this first study on this topic, the Q-switched ruby laser was superior to the ablative CO2 fractional laser in the treatment of lentigines solares on the dorsum of hands.

Citations

Jun 25, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Laurence ImhofMarjam J Barysch
Apr 21, 2016·Lasers in Surgery and Medicine·Vasanop VachiramonKumutnart Chanprapaph
Apr 30, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kimberly Butterwick, Neil Sadick
Sep 26, 2020·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Edward Victor Ross
Sep 15, 2018·Clinical Case Reports·Giuseppe ScarcellaMichael Canova Engelbrecht Nielsen
Oct 20, 2019·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sergio Del Río-SanchoMaría José Alonso

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