LASI-DAD study: a protocol for a prospective cohort study of late-life cognition and dementia in India

BMJ Open
Jinkook LeeA B Dey

Abstract

Alzheimer's disease and related dementias can be considered the epidemic of the 21st century. Particularly, the predicted growth in the size of elderly populations in low-income and middle-income countries is expected to produce a dramatic surge in dementia prevalence and incidence. Although a rising burden of dementia presents an urgent challenge for India, previous efforts to study dementia in the country have relied on non-representative samples in geographically restricted regions. The Harmonised Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) will provide rich, population-representative data on late-life cognition and dementia and their risk factors for the first time in India. The LASI-DAD will recruit a sample of 3000 people aged 60+ years. Their family members or friends, whom respondents nominate as informants, participate in the computer-assisted personal interview. The study sample is drawn from the ongoing, nationally representative Longitudinal Aging Study in India, a multipurpose panel survey of aging. We aim to collect rich data on cognitive and neuropsychological tests, informant reports, and epidemiological data through a comprehensive geriatric assessment, and venous bloo...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Feb 1, 1991·Journal of the American Geriatrics Society·D Podsiadlo, S Richardson
Jul 1, 1968·The British Journal of Psychiatry : the Journal of Mental Science·G BlessedM Roth
Nov 1, 1984·The American Journal of Psychiatry·W G RosenK L Davis
Jul 2, 2002·American Journal of Respiratory and Critical Care Medicine·UNKNOWN ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories
Mar 22, 2003·Lancet·Martin PrinceUNKNOWN 10/66 Dementia Research Group
Dec 1, 1962·Brain : a Journal of Neurology·E DE RENZI, L A VIGNOLO
Apr 9, 2005·Journal of the American Geriatrics Society·Ziad S NasreddineHoward Chertkow
Jul 31, 2007·BMC Public Health·Martin PrinceRichard Uwakwe
Jan 25, 2011·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·David R WeirMary Sano
Jul 16, 2011·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Stefan Agrigoroaei, Margie E Lachman
Mar 17, 2012·International Psychogeriatrics·James T BeckerMary Ganguli
Apr 5, 2013·The New England Journal of Medicine·Michael D HurdKenneth M Langa
Jul 23, 2013·Indian Journal of Public Health·Girish N Rao, Srikala Bharath
Oct 2, 2013·Indian Journal of Psychiatry·Ravikesh TripathiMathew Varghese

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Citations

Aug 21, 2020·Journal of the American Geriatrics Society·Jinkook LeeAparajit B Dey
Aug 21, 2020·Journal of the American Geriatrics Society·Marco AngrisaniJinkook Lee
Aug 21, 2020·Journal of the American Geriatrics Society·Jinkook LeeAparajit B Dey
Aug 21, 2020·Journal of the American Geriatrics Society·Alden L GrossJudith A Saxton
Aug 21, 2020·Journal of the American Geriatrics Society·Madeline R FarronKenneth M Langa
Oct 23, 2020·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·Agustin IbanezJennifer S Yokoyama
Apr 17, 2021·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Jinkook LeeUNKNOWN Gateway to Global Aging Data Team

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Methods Mentioned

BETA
genotyping
blood draws
blood draw

Software Mentioned

DAD
LASI

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