Late complications and survival of endoprosthetic reconstruction after resection of bone tumors.

Clinical Orthopaedics and Related Research
Ahmad ShehadehRobert Henshaw

Abstract

While complications following massive endoprosthetic reconstruction have been previously described, the incidence and effects of these complications over extended periods of time have not been well characterized in large series. We therefore determined: (1) incidence and types of complications; (2) relative risk of complications; (3) likelihood of secondary complications; (4) whether modularity altered such complications; (5) implant failure and limb salvage rates and (6) implant survival over extended followup. We retrospectively reviewed 232 patients (241 implants: 50 custom,191 modular) who underwent endoprosthetic reconstruction for malignant and aggressive bone tumors between 1980 and 2002. Complications were classified as infection, mechanical, superficial soft tissue, deep soft tissue, or dislocation. Survival was determined by Kaplan-Meier analysis. Minimum followup was 5 years (mean: 10 years; range: 5-27 years). One hundred thirty-seven of 232 patients (59%) underwent a single reconstruction. Ninety-five patients had 242 additional procedures. Forty-four revised patients retained their original prosthesis. Limb salvage rate was 90%; implant failure (removal of the cemented part) was seen in 29% (70/241) with a median ...Continue Reading

References

Jan 1, 1980·Archives of Orthopaedic and Trauma Surgery·M BosquetJ C Mulier
Aug 1, 1995·The Journal of Bone and Joint Surgery. American Volume·M M Malawer, L B Chou
Aug 12, 1998·The Journal of Bone and Joint Surgery. British Volume·H AkazawaH Inoue
Jun 15, 2000·Clinical Orthopaedics and Related Research·J BickelsM M Malawer
Jul 14, 2001·Clinical Orthopaedics and Related Research·F MittermayerR Kotz
Feb 1, 2002·International Orthopaedics·I IlyasD A Younge
Jun 20, 2002·Clinical Orthopaedics and Related Research·Jacob BickelsMartin M Malawer
Apr 2, 2004·Clinical Orthopaedics and Related Research·Erik N ZeegenHenry J Mankin
Apr 5, 2005·The Journal of Bone and Joint Surgery. American Volume·L M JeysR M Tillman
May 13, 2006·Clinical Orthopaedics and Related Research·Georg GoshegerJendrik Hardes
May 25, 2006·The Journal of Bone and Joint Surgery. British Volume·E R AhlmannH Gotha
Feb 13, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·I-W SimP F M Choong
Feb 24, 2009·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·Lee Jeys, Robert Grimer
Mar 19, 2009·Orthopedics·Steven GitelisSusan Shott

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Citations

Jun 27, 2013·World Journal of Surgical Oncology·Dongqing ZuoZhengdong Cai
Jun 9, 2012·BMC Musculoskeletal Disorders·Khaled HasanMichelle Ghert
Jan 25, 2013·AJR. American Journal of Roentgenology·Corey J ChakarunDakshesh B Patel
May 15, 2015·Orthopedics·Panagiotis TsagkozisHenrik C F Bauer
Mar 27, 2015·Surgical Infections·Andreas F MavrogenisPietro Ruggieri
Jun 6, 2015·Surgical Infections·Amreeta DhanoaHassan Elbahri
Feb 20, 2015·BioMed Research International·Gregor HauschildSteffen Höll
Sep 26, 2015·BMC Musculoskeletal Disorders·Guntmar GradlChlodwig Kirchhoff
Jan 27, 2017·Acta Orthopaedica·Minna LaitinenAntti Eskelinen
Dec 14, 2016·BMC Musculoskeletal Disorders·Andreas ToepferHeinz Mühlhofer
Dec 8, 2011·Orthopedics·Andreas F MavrogenisPietro Ruggieri
Jun 24, 2017·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Jan Lesensky, Daniel E Prince
Oct 5, 2011·Clinical Orthopaedics and Related Research·Patrick F BerginRobert M Henshaw
Sep 25, 2010·Der Orthopäde·R Ascherl
Oct 30, 2014·The Open Orthopaedics Journal·Anthippi Gkavardina, Panagiotis Tsagozis
Mar 25, 2015·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·C RadtkeP Vogt
Mar 7, 2014·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H-U SteinauL Podleska
Jun 27, 2014·Clinical Orthopaedics and Related Research·Rodolfo CapannaDomenico Andrea Campanacci
Oct 12, 2014·Journal of Pediatric Orthopedics. Part B·Rebecca TateJuliet Hale
May 27, 2014·American Society of Clinical Oncology Educational Book·Robert M Henshaw
Apr 11, 2014·The Oncologist·Lizz van der HeijdenHans Gelderblom
Jun 30, 2019·Acta orthopaedica et traumatologica turcica·Laura CampanacciDavide Maria Donati
May 28, 2019·Der Orthopäde·H FritzscheK-D Schaser
Sep 1, 2017·Clinical Orthopaedics and Related Research·Patricia Jacqueline SchneiderMichelle Ghert
Sep 10, 2015·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Matthew T HoudekFranklin H Sim
Jan 24, 2017·Orthopedics·Olga D SavvidouPanayiotis J Papagelopoulos
May 1, 2019·The Bone & Joint Journal·M R MedellinL Jeys
Mar 3, 2020·Frontiers in Bioengineering and Biotechnology·Luciano VidalPierre Layrolle
Jan 20, 2017·Oncology Letters·Aneta BorkowskaPiotr Rutkowski
Jan 23, 2021·Skeletal Radiology·Imran KhanAsif Saifuddin
Mar 7, 2014·The Journal of Bone and Joint Surgery. American Volume·Lizz van der HeijdenP D Sander Dijkstra
Feb 5, 2021·Zeitschrift für Orthopädie und Unfallchirurgie·Mohamed GhanemAndreas Roth

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