Late components of the event-related potentials and their topography in Parkinson's disease

Movement Disorders : Official Journal of the Movement Disorder Society
J LagopoulosJ G Morris

Abstract

Late components of the event-related potential (ERP; N100, P200, N200, and P300) were elicited using an auditory oddball paradigm (with a button-press response to target stimuli) in 15 Parkinson's disease (PD) patients and 50 normal control subjects. Compared with control subjects, PD subjects showed a significant decrease in N200 amplitude. Between-group topographical differences in N200 amplitude were evident at central (C3, Cz, C4) and temporal (T5, T3, T4, T6) regions. The results may reflect a deficit in response selection in PD possibly resulting from a dysfunction associated with the abnormalities in the central and temporal regions found to have a decreased N200 amplitude compared with normal control subjects in this study.

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Citations

Feb 28, 2001·Annals of Neurology·M R DeLong, T Wichmann
Sep 29, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·A HozumiK Yamazaki
Jan 26, 2002·Journal of the Neurological Sciences·R MontirossoN Bresolin
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Aug 9, 2020·Frontiers in Neurology·Evelien De GrooteMiet De Letter
Nov 24, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kayla B StefanidisMathew J Summers

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