May 27, 2014

Late-life depression and cardiovascular disease burden: examination of reciprocal relationship

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Namkee G ChoiG John Chen


Empirical studies of the relationship between depression and cardiovascular disease (CVD) tend to be limited to examination of one-way relationships. This study assessed both cross-sectional association and longitudinal reciprocal relationships between late-life depressive symptoms and CVD. The National Health and Aging Trends Study waves 1 (T1) and 2 (T2, one year later) provided the data. The study sample (N = 5,414) represented Medicare beneficiaries aged 65 years or older. We fit structural equation models to examine: 1) cross-sectional association between depression and CVD at each wave; and 2) longitudinal reciprocal relationship between T1 depression and T2 CVD and between T1 CVD and T2 depression. At T1, 28.6% reported a CVD diagnosis, and at T2, 4.9% reported having had a new diagnosis or new episode of heart attack or heart disease and 2.2% reported having had a stroke since T1. In addition to significant cross-sectional relationships between depression and CVD, T1 CVD had significant impact on T2 depressive symptoms, and T1 depressive symptoms had significant impact on T2 CVD, with a 1-point increase in depressive symptom score increasing the odds of having a new CVD diagnosis or episode by 21%. The care of older adu...Continue Reading

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Mentioned in this Paper

Prevalence Studies
Excessive Attrition of Teeth
Depressed - Symptom
Chronic Disease
Myocardial Infarction
Alzheimer's Disease
New Diagnosis Procedure
Cardiovascular Diseases
Longitudinal Survey
Hypertensive Disease

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