May 27, 2014

Late-life depression and cardiovascular disease burden: examination of reciprocal relationship

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Namkee G ChoiG John Chen

Abstract

Empirical studies of the relationship between depression and cardiovascular disease (CVD) tend to be limited to examination of one-way relationships. This study assessed both cross-sectional association and longitudinal reciprocal relationships between late-life depressive symptoms and CVD. The National Health and Aging Trends Study waves 1 (T1) and 2 (T2, one year later) provided the data. The study sample (N = 5,414) represented Medicare beneficiaries aged 65 years or older. We fit structural equation models to examine: 1) cross-sectional association between depression and CVD at each wave; and 2) longitudinal reciprocal relationship between T1 depression and T2 CVD and between T1 CVD and T2 depression. At T1, 28.6% reported a CVD diagnosis, and at T2, 4.9% reported having had a new diagnosis or new episode of heart attack or heart disease and 2.2% reported having had a stroke since T1. In addition to significant cross-sectional relationships between depression and CVD, T1 CVD had significant impact on T2 depressive symptoms, and T1 depressive symptoms had significant impact on T2 CVD, with a 1-point increase in depressive symptom score increasing the odds of having a new CVD diagnosis or episode by 21%. The care of older adu...Continue Reading

  • References39
  • Citations7

References

Mentioned in this Paper

Prevalence Studies
Excessive Attrition of Teeth
Depressed - Symptom
Chronic Disease
Myocardial Infarction
Alzheimer's Disease
New Diagnosis Procedure
Cardiovascular Diseases
Longitudinal Survey
Hypertensive Disease

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Related Papers

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Benjamin T MastPeter A Lichtenberg
The British Journal of Psychiatry : the Journal of Mental Science
M Lester, M Blanchard
Psychopharmacology Bulletin
L W ThompsonD Gallagher
© 2020 Meta ULC. All rights reserved