Late onset autoimmune thrombocytopenia associated with pegylated interferon-alpha-2b plus ribavirin treatment for chronic hepatitis C

Journal of Gastroenterology and Hepatology
Ioannis S ElefsiniotisChristos Mavrogiannis

Abstract

Interferon-induced, immune-mediated, thrombocytopenia is a rare event. In this report the case is described of development of severe, reversible, autoimmune thrombocytopenia in a patient with chronic hepatitis C virus infection, 6 months after the discontinuation of pegylated interferon-alpha-2b plus ribavirin treatment. Physicians must be aware that autoimmune thrombocytopenia can occur even after the end of treatment, as a late onset complication, especially when using the pegylated forms of interferons, which have longer half-lives and prolonged activity.

References

Jun 30, 1998·Acta Haematologica·F HernándezA Cerveró
Mar 26, 2002·Digestive Diseases and Sciences·Abdurrahman SagirDieter Häussinger
Apr 30, 2002·Acta Haematologica·Pia Raanani, Isaac Ben-Bassat
Mar 26, 2003·The American Journal of Gastroenterology·V A SevastianosE K Manesis

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Citations

Feb 27, 2013·Journal of Pediatric Gastroenterology and Nutrition·Jean P MollestonUNKNOWN PEDS-C Clinical Research Network
Mar 20, 2010·World Journal of Gastroenterology : WJG·Li LiJun Lu
Aug 21, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Laurent CotteUNKNOWN French National Agency for Research on AIDS and Viral Hepatitis (ANRS) HC26 Study Group
Jul 30, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·Masaru EnomotoNorifumi Kawada
Apr 20, 2007·Internal Medicine·Hiroki TaharaMasatomo Mori
Mar 9, 2013·Toxicologic Pathology·Nancy E Everds, Jacqueline M Tarrant

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