PMID: 15252348Jul 15, 2004Paper

Late-onset blebitis/endophthalmitis: incidence and outcomes with mitomycin C

Optometry and Vision Science : Official Publication of the American Academy of Optometry
Elizabeth Draper Muckley, Richard A Lehrer

Abstract

To assess the outcomes of patients who had late infections after undergoing filtering surgery with mitomycin C with respect to treatment, resultant vision, and maintenance of intraocular pressure. A retrospective review of 233 eyes that underwent trabeculectomy with mitomycin C with or without coincident cataract extraction and intraocular lens insertion from August 1993 to June 1997 was undertaken. Records were examined for postoperative infection occurring at least 6 months after filtering surgery. Age, sex, date, and type of surgery were reviewed and entered into a computerized database. Bleb infections occurred in 6 of 233 (2.6%) eyes that underwent mitomycin C filtering surgery. Four of these developed endophthalmitis. The average postoperative time until infection was 24.7 months. Two patients had bleb leaks, one of which progressed to endophthalmitis. On resolution of infection, all blebs remained functional, and vision returned to preblebitis acuities in 67%. Aggressive topical antibiotic therapy with daily observation may be appropriate in selected cases of late-onset blebitis and endophthalmitis. Eyes may continue to have good visual outcomes and functioning filters without need for additional surgery or hospitalizati...Continue Reading

References

Nov 1, 1979·American Journal of Ophthalmology·F D'ErmoD Doro
Nov 1, 1992·Archives of Ophthalmology·P A Campochiaro, W R Green
Jul 1, 1985·Ophthalmology·S MandelbaumW Culbertson
Jan 1, 1986·Ophthalmology·K A LampingS I Afran
Nov 1, 1995·Archives of Ophthalmology·E C Alfonso, H W Flynn
Jan 1, 1994·Archives of Ophthalmology·S P DonahueB H Jewart
Jan 1, 1994·Archives of Ophthalmology·R H BrownL A Wilson
Apr 1, 1996·Ophthalmology·E J HigginbothamG L Skuta
Aug 1, 1996·Archives of Ophthalmology·D S GreenfieldH W Flynn
Sep 23, 1997·Archives of Ophthalmology·P P ChenR K Parrish
May 2, 1998·Archives of Ophthalmology·D S GreenfieldR Ritch
Aug 27, 1999·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·A SolomonJ Frucht-Pery
Oct 28, 1999·Current Opinion in Ophthalmology·N S BorisuthT Krupin
Mar 18, 2000·Archives of Ophthalmology·J B SoltauR Ritch
Jul 27, 2001·Archives of Ophthalmology·H D JampelUNKNOWN Glaucoma Surgical Outcomes Study Group
Apr 5, 2002·American Journal of Ophthalmology·Rookaya MatherRegis P Kowalski
Jul 3, 2002·Ophthalmology·Rajiv BindlishRichard Lehrer
Sep 25, 2002·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G KrommesF Grehn

❮ Previous
Next ❯

Citations

May 14, 2010·Clinical Ophthalmology·Takeo FukuchiHaruki Abe
Jun 6, 2009·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Sapna SharanYvonne M Buys
Aug 8, 2015·Acta Ophthalmologica·Sanaa A Yassin
Oct 2, 2014·Acta Ophthalmologica·Matthias C GrieshaberRobert Stegmann
Apr 13, 2017·The British Journal of Ophthalmology·Poornima A RaiIan E Murdoch
Nov 11, 2006·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·A PirouzianY Jockin
Jan 1, 2016·Current Opinion in Ophthalmology·Behzad AmoozgarJane Kuo
Sep 1, 2015·International Ophthalmology Clinics·David A Solá-Del ValleLucy Q Shen
Jul 14, 2020·Journal of Ophthalmology·Hideyuki NakanoTakeo Fukuchi
Sep 12, 2018·International Journal of Retina and Vitreous·Niroj Kumar SahooJay Chhablani
Apr 18, 2009·Journal of Glaucoma·Claes H DohlmanMarlene Durand
Sep 10, 2019·Journal of Current Glaucoma Practice·Cooper D RodgersMark B Sherwood
Apr 10, 2007·Journal français d'ophtalmologie·O OuhadjM T Nouri

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.