PMID: 9532536Apr 9, 1998Paper

Late-onset Leber's hereditary optic neuropathy

Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
E T Ajax, R Kardon

Abstract

Progressive, sequential visual loss in the left and then right eye was reported in a 73-year-old male over three months. The presence of a family history of visual loss and the lack of other findings in association with bilateral cecocentral scotomata led to a diagnosis of new onset Leber's hereditary optic neuropathy, confirmed by the presence of a mutation at the 11,778 position. This case illustrates that Leber's hereditary optic neuropathy may manifest late in life.

Citations

Jul 16, 2010·Journal of Neurology·Stefano ZoccolellaLuigi Maria Specchio
Feb 14, 2004·American Journal of Ophthalmology·Federico SadunAlfredo A Sadun
Feb 10, 2004·Progress in Retinal and Eye Research·Valerio CarelliAlfredo A Sadun
May 12, 2005·Optometry : Journal of the American Optometric Association·Connie L ChronisterStephen J Merckle
Oct 24, 2014·Orphanet Journal of Rare Diseases·Konstantin DimitriadisThomas Klopstock
Jul 20, 2010·Neurologic Clinics·Karl Golnik
Jun 24, 2008·Survey of Ophthalmology·Vinay A ShahRod Foroozan
Apr 3, 2002·Ophthalmology·Oliver Bergamin, Randy H Kardon
Jun 20, 2008·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Lora R DagiDean M Cestari

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