Late-onset Neonatal Infections 1997 to 2017 Within a Cohort in Western Sweden-The Last 21 Years of a 43-Year Surveillance.

The Pediatric Infectious Disease Journal
Margrét Johansson GudjonsdottirAnders Elfvin

Abstract

The objective of the study was to assess the epidemiology of late-onset (LO) neonatal invasive infections with surveillance covering 43 years, starting from 1975. Observational epidemiologic, retrospective study including a cohort of infants born in western Sweden in 1997-2017, who had a positive blood and cerebral spinal fluid culture between 3 and 120 days of age. A comparison was made of the incidence between 1997-2007 and 2008-2017. Data on LO infections during 3-27 days of life were assessed from 1975. A total of 473 cases of LO infections were registered in 437 patients. The incidence increased from 2.0 to 3.1/1000 live births (LB) between 1997-2007 and 2008-2017 (P < 0.001). The increase in incidence was most pronounced among infants born <28 weeks gestation (from 255 to 398/1000 LB, P < 0.001). The most frequent pathogens were Staphylococcus aureus (25%), coagulase-negative staphylococci (17%), and Escherichia coli (13%). Infections due to group B Streptococci rose from 0.16/1000 LB to 0.33 (P = 0.03). During the whole surveillance period from 1975 to 2017, there were 579 cases between 3 and 27 days of life. Although the incidence increased in 2008-2017 to 1.9/1000 LB after first declining in 1997-2007, the case-fatalit...Continue Reading

References

Nov 1, 1990·Acta paediatrica Scandinavica·I TessinK Thiringer
Nov 26, 2002·Paediatric and Perinatal Epidemiology·Monique Trijbels-SmeuldersLouis A A Kollée
Jul 20, 2004·Clinical Microbiology Reviews·David Kaufman, Karen D Fairchild
Nov 18, 2004·JAMA : the Journal of the American Medical Association·Barbara J StollUNKNOWN National Institute of Child Health and Human Development Neonatal Research Network
Sep 6, 2005·Pediatrics·Matthew J BizzarroPatrick G Gallagher
Nov 18, 2005·Journal of Perinatology : Official Journal of the California Perinatal Association·S SarkarA R Spitzer
May 10, 2006·Pediatrics·Kirsten FlueggeUNKNOWN German Pediatric Surveillance Unit Study Group
Sep 30, 2010·Archives of Disease in Childhood. Fetal and Neonatal Edition·Stefania VergnanoPaul T Heath
Jul 15, 2011·The Pediatric Infectious Disease Journal·Guđrún Lilja ÓladóttirÁsgeir Haraldsson
Nov 19, 2011·FEMS Microbiology Reviews·Antony CroxattoGilbert Greub
Mar 13, 2012·Journal of Paediatrics and Child Health·Majeda S HammoudDavid Isaacs
Jan 9, 2013·Pediatrics·Alberto BerardiUNKNOWN GBS Prevention Working Group, Emilia-Romagna
Jan 18, 2013·The Journal of Pediatrics·Nansi S BoghossianUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Jul 24, 2013·Pediatrics·Ayoub MithaUNKNOWN EPIPAGE Study Group
Aug 1, 2013·The Pediatric Infectious Disease Journal·Ming-Horng TsaiYhu-Chering Huang
May 7, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M-H TsaiY-C Huang
Nov 27, 2014·Archives of Disease in Childhood. Fetal and Neonatal Edition·Ying Dong, Christian P Speer
Jan 6, 2015·Bulletin of the World Health Organization·Shefali OzaSimon N Cousens
Apr 29, 2015·The Journal of Pediatrics·Matthew J BizzarroPatrick G Gallagher
Sep 17, 2016·The Lancet Infectious Diseases·Elizabeth J A FitchettUNKNOWN SPRING (Strengthening Publications Reporting Infection in Newborns Globally) Group
Feb 9, 2017·The Pediatric Infectious Disease Journal·Harsha GowdaYogavijayan Kandasamy
Feb 1, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Amélie CollinsJames L Wynn

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

© 2021 Meta ULC. All rights reserved