Late-onset transconjunctival oozing and point leak of aqueous humor from filtering bleb after trabeculectomy

American Journal of Ophthalmology
Hiroshi MatsuoMakoto Araie

Abstract

To estimate the prevalence and identify factors related to late-onset transconjunctival aqueous oozing and point leak from functioning blebs after trabeculectomy with 5-fluorouracil (5-FU) or mitomycin C. Cross-sectional study. The study took place at the outpatient clinic of the Department of Ophthalmology, University of Tokyo Graduate School of Medicine (Tokyo, Japan). Four hundred three consecutive patients (403 eyes) with functional blebs at least 3 months after previously performed trabeculectomy were examined between December 1997 and February 1998. The Seidel test was performed with extended observation up to 15 seconds. Oozing was identified as transconjunctival aqueous egress without interruption of the conjunctival tissue or aqueous stream on the bleb wall. Logistic regression analyses of oozing and point leak in 331 eyes with an avascular area were performed using independent variables, including age, gender, glaucoma diagnosis, prior incisional surgery, antimetabolite use, combined cataract surgery, postoperative follow-up period, intraocular pressure (IOP), concurrent glaucoma therapy, bleb size, and avascular area size. Of 403 eyes, 48 eyes (11.9%) had oozing and 8 eyes (2.0%) had point leak. Intraocular pressure ...Continue Reading

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Citations

May 14, 2010·Clinical Ophthalmology·Takeo FukuchiHaruki Abe
Apr 7, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Holger Mietz, Günter K Krieglstein
Aug 14, 2012·Acta Ophthalmologica·Tetsuya YamamotoUNKNOWN Study Group for the Japan Glaucoma Society Survey of Bleb-related Infection
Jul 4, 2013·Acta Ophthalmologica·Tetsuya YamamotoUNKNOWN Japan Glaucoma Society Survey of Bleb-related Infection
Oct 27, 2015·Journal of Ophthalmology·Kazuyoshi OhtomoMiyuki Nagahara
Dec 10, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kei-Ichi NakashimaHidenobu Tanihara
Oct 12, 2010·Ophthalmology·Tetsuya YamamotoUNKNOWN Collaborative Bleb-related Infection Incidence and Treatment Study Group
Mar 5, 2005·Eye·N Anand, C Atherley
Aug 19, 2007·Journal of Glaucoma·Nitin Anand, Seema Arora
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Sep 14, 2012·The Cochrane Database of Systematic Reviews·Frank Bochmann, Augusto Azuara-Blanco

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