Late presenters to HIV care and treatment, identification of associated risk factors in HIV-1 infected Indian population.

BMC Public Health
Kamalika MojumdarSanjay Mendiratta

Abstract

Timely access to antiretroviral therapy is a key to controlling HIV infection. Late diagnosis and presentation to care diminish the benefits of antiretrovirals and increase risk of transmission. We aimed to identify late presenters in patients sent for first CD4 T cell count after HIV diagnosis, for therapy initiation evaluation. Further we aimed at identifying patient factors associated with higher risk of late presentation. Retrospective data collection and analysis was done for 3680 subjects visiting the laboratory for CD4 T cell counts between 2001 and 2007. We segregated the patients on basis of their CD4 T cell counts after first HIV diagnosis. Factors associated with risk of late presentation to CD4 T cell counts after HIV diagnosis were identified using univariate analysis, and the strength of association of individual factor was assessed by calculation of odds ratios. Of 3680 subjects, 2936 (83.37%) were defined as late presenters. Late testing varied among age groups, transmission categories, and gender. Males were twice as likely to present late as compared to females. We found significant positive association of heterosexual transmission route (p < 0.001), and older age groups of 45 years and above (p = 0.0004) to l...Continue Reading

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Citations

Sep 13, 2013·BMC Infectious Diseases·Yinzhong ShenJiangrong Wang
Feb 5, 2013·Journal of Health Care for the Poor and Underserved·Maria LahuertaDenis Nash
Mar 5, 2013·PloS One·Duc Bui NguyenBruce Baird Struminger
Mar 26, 2014·AIDS Patient Care and STDs·Mary Jo TrepkaSpencer Lieb
Jan 6, 2012·AIDS and Behavior·Abraham MukoloKenneth A Wallston
Feb 11, 2015·International Journal of Geriatric Psychiatry·Chunqing LinWu Jie
Sep 29, 2015·AIDS Research and Human Retroviruses·Su Jin JeongJun Yong Choi
Dec 3, 2014·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Kudakwashe C TakarindaOwen Mugurungi
May 5, 2016·BMC Public Health·Howard NyikaMufuta Tshimanga
Dec 1, 2017·Journal of the International Association of Providers of AIDS Care·Deepak MadiPriya Rathi
Sep 19, 2018·The American Journal of Tropical Medicine and Hygiene·Satish RaoAvinash K Shetty
Dec 6, 2016·Infectious Diseases of Poverty·Hailay GesesewLillian Mwanri

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