Late small bowel toxicity after adjuvant treatment for rectal cancer

International Journal of Colorectal Disease
Matthias Guckenberger, M Flentje

Abstract

For locally advanced rectal cancer surgery as sole treatment results in poor local control and survival. After adjuvant radiotherapy for locally advanced rectal cancer, small bowel toxicity has been the most frequent and serious side effect. The gain in survival and local control was accompanied by severe late chronic toxicity reducing the benefit of adjuvant treatment. Clinical factors, pathology and treatment of late small bowel toxicity after adjuvant radiotherapy for locally advanced rectal cancer will be discussed. This review will focus on different surgical and radiotherapeutic means reducing the risk of late small bowel damage.

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Citations

Feb 7, 2007·Future Oncology·Matthias Guckenberger, Michael Flentje
Dec 8, 2007·International Journal of Colorectal Disease·Lutz MoserStefan Höcht
Jul 9, 2008·Acta Oncologica·Katrine J Emmertsen, Søren Laurberg
Dec 30, 2010·Scandinavian Journal of Gastroenterology·H Jervoise N AndreyevMartin Hauer-Jensen
Aug 27, 2010·Journal of Surgical Oncology·Yoichiro HommaYasuyuki Kobayashi
Aug 2, 2006·International Journal of Radiation Oncology, Biology, Physics·Lye Mun ThoAlexander C McDonald
May 5, 2010·Oncology Nursing Forum·Sunita Bayyavarapu Bapuji, Jo-Ann V Sawatzky

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