Latent class analysis of early developmental trajectory in baby siblings of children with autism.

Journal of Child Psychology and Psychiatry, and Allied Disciplines
Rebecca J LandaMargaret Bauman

Abstract

Siblings of children with autism (sibs-A) are at increased genetic risk for autism spectrum disorders (ASD) and milder impairments. To elucidate diversity and contour of early developmental trajectories exhibited by sibs-A, regardless of diagnostic classification, latent class modeling was used. Sibs-A (N = 204) were assessed with the Mullen Scales of Early Learning from age 6 to 36 months. Mullen T scores served as dependent variables. Outcome classifications at age 36 months included: ASD (N = 52); non-ASD social/communication delay (broader autism phenotype; BAP; N = 31); and unaffected (N = 121). Child-specific patterns of performance were studied using latent class growth analysis. Latent class membership was then related to diagnostic outcome through estimation of within-class proportions of children assigned to each diagnostic classification. A 4-class model was favored. Class 1 represented accelerated development and consisted of 25.7% of the sample, primarily unaffected children. Class 2 (40.0% of the sample), was characterized by normative development with above-average nonverbal cognitive outcome. Class 3 (22.3% of the sample) was characterized by receptive language, and gross and fine motor delay. Class 4 (12.0% of ...Continue Reading

References

Sep 1, 1977·Journal of Child Psychology and Psychiatry, and Allied Disciplines·S Folstein, M Rutter
Mar 1, 1985·Journal of the American Academy of Child Psychiatry·H Kurita
Sep 1, 1995·JPEN. Journal of Parenteral and Enteral Nutrition·J L Mullen
Jun 1, 2000·Journal of Autism and Developmental Disorders·M DavidovitchM P Safir
Apr 13, 2001·Pediatric Neurology·S ShinnarF R Volkmar
Apr 25, 2001·Biometrics·B Muthén, K Shedden
Oct 3, 2001·Pediatrics·E Fombonne, S Chakrabarti
May 28, 2002·Development and Psychopathology·Julie A OsterlingJeffrey A Munson
Aug 23, 2003·Biostatistics·Bengt MuthénJason Liao
Jan 13, 2004·Journal of Autism and Developmental Disorders·Wendy A GoldbergM Anne Spence
Feb 26, 2005·Psychopathology·S MaestroC Sommario
Mar 8, 2005·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Lonnie ZwaigenbaumPeter Szatmari
Mar 31, 2005·Journal of Autism and Developmental Disorders·Annelies de BildtRuud Minderaa
Aug 27, 2005·Journal of Autism and Developmental Disorders·Emily WernerJulie Osterling
Nov 17, 2005·Autism : the International Journal of Research and Practice·Sally OzonoffRebecca Landa
May 23, 2006·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Rebecca Landa, Elizabeth Garrett-Mayer
Aug 17, 2006·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Siobhan E ColganGrace T Baranek
Sep 19, 2006·Journal of Clinical Epidemiology·A Rogier T DondersKarel G M Moons
Jan 11, 2007·Journal of Autism and Developmental Disorders·Susan E BrysonCatherine McDermott
Jan 12, 2007·Journal of Autism and Developmental Disorders·Michelle SullivanRebecca Landa
Jul 4, 2007·Archives of General Psychiatry·Rebecca J LandaElizabeth Garrett-Mayer
May 2, 2008·Journal of Autism and Developmental Disorders·Gillian BairdEmily Simonoff
Sep 23, 2008·Autism : the International Journal of Research and Practice·J BrianL Zwaigenbaum
Mar 28, 2009·Journal of Autism and Developmental Disorders·Ifat GamlielMarian Sigman
Jul 7, 2009·Nature Neuroscience·Courtney C HaswellReza Shadmehr
Dec 2, 2009·The British Journal of Psychiatry : the Journal of Mental Science·R A HoekstraA Ronald
Apr 23, 2010·Journal of the American Academy of Child and Adolescent Psychiatry·Sally OzonoffGregory S Young
May 12, 2010·Journal of Child Psychology and Psychiatry, and Allied Disciplines·A N BhatR J Landa
Jul 20, 2010·Psychometrika·Albert Satorra, Peter M Bentler
Oct 5, 2010·The American Journal of Psychiatry·John N ConstantinoPaul Law
Jan 31, 2012·Current Biology : CB·Mayada ElsabbaghUNKNOWN BASIS Team
Mar 1, 2012·The American Journal of Psychiatry·Jason J WolffUNKNOWN IBIS Network
Aug 25, 2012·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Joanne E FlanaganMargaret Bauman
Mar 1, 2001·Pediatric Neurology·Shlomo ShinnarFred R Volkmar

❮ Previous
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Citations

Oct 1, 2013·Lancet·Meng-Chuan LaiSimon Baron-Cohen
Feb 13, 2016·Journal of Autism and Developmental Disorders·Jane E RobertsDonald B Bailey
Apr 8, 2015·Developmental Science·Michael S C ThomasTony Charman
Mar 5, 2013·Journal of the American Academy of Child and Adolescent Psychiatry·Daniel MessingerMarian Sigman
Dec 22, 2015·Autism Research : Official Journal of the International Society for Autism Research·Jessica A BrianSusan E Bryson
Jul 1, 2014·Child Development·Klaus LibertusRebecca J Landa
Jun 21, 2015·Neuroscience and Biobehavioral Reviews·Valeria CostanzoFabio Apicella
Jun 13, 2015·Health Technology Assessment : HTA·Helen McConachieKatrina Williams
Jul 25, 2013·Journal of the American Academy of Child and Adolescent Psychiatry·Whitney GuthrieCatherine Lord
Oct 19, 2014·Journal of Autism and Developmental Disorders·Maurice A FeldmanXudong Liu
May 28, 2014·Trends in Cognitive Sciences·Lisa ByrgeLinda B Smith
Apr 17, 2013·Behavioural Brain Research·Lonnie ZwaigenbaumNancy Garon
Dec 24, 2013·Neuroscience and Biobehavioral Reviews·Emily J H JonesMark H Johnson
Oct 9, 2014·Frontiers in Psychology·Klaus Libertus, Rebecca J Landa
Jan 27, 2015·Early Human Development·Jessica P BentzleyDorothea Jenkins
Sep 13, 2014·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Cara R DamianoGabriel S Dichter
Jul 16, 2016·Autism Research : Official Journal of the International Society for Autism Research·Tony CharmanLonnie Zwaigenbaum
Jan 14, 2017·International Journal of Speech-language Pathology·Andrew J O Whitehouse
Feb 10, 2017·Autism Research : Official Journal of the International Society for Autism Research·Fadila SerdarevicHenning Tiemeier
May 15, 2016·Autism : the International Journal of Research and Practice·Amanda BrignellAngela T Morgan
Mar 25, 2017·Autism Research : Official Journal of the International Society for Autism Research·Karen Chenausky, Helen Tager-Flusberg
Mar 3, 2018·International Review of Psychiatry·John N Constantino
May 1, 2018·Journal of Autism and Developmental Disorders·Amanda BrignellAngela T Morgan
Jan 30, 2018·Autism : the International Journal of Research and Practice·Eric RubensteinJulie Daniels
Nov 27, 2018·Autism Research : Official Journal of the International Society for Autism Research·Niamh PearsonFiona S McEwen
Jan 10, 2019·Autism Research : Official Journal of the International Society for Autism Research·A M KellermanS P Lane
Sep 26, 2013·Journal of Neurodevelopmental Disorders·Nava Levit-BinnunYulia Golland
Oct 26, 2018·Pediatric Research·John N Constantino
Jan 5, 2019·Maternal & Child Nutrition·Charlotte E LaneLinda S Adair
Aug 15, 2017·Development and Psychopathology·Elizabeth C BaconKaren Pierce
Aug 14, 2019·International Journal of Language & Communication Disorders·Eva BruyneelHerbert Roeyers
Sep 6, 2017·Journal of Neurodevelopmental Disorders·Sabine E MousJohn N Constantino

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