Latent polyglandular autoimmune syndrome type 2 case diagnosed during a shock manifestation

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Eren GürkanBeyza Kocabaş

Abstract

There are many types of polyglandular autoimmune syndrome (PAS). PAS type 2 is the most common type among adults. For PAS type 2 (PAS-2) diagnosis, detection of Addison's disease with autoimmune thyroid disease and/or type 1 diabetes mellitus are required. Premature ovarian insufficiency, pernicious anemia, vitiligo, alopecia, myasthenia gravis, celiac disease and autoimmune diabetes insipidus may be comorbidities of this condition. Contrary to the common belief, latent PAS is more common than the manifest forms. Here, we present a PAS-2 case diagnosed via adrenal crisis. At the time of diagnosis, the case was observed to have thyroid, adrenal and ovarian involvement. Therefore, PAS-2 and possible immunologic disorders were discussed.

References

Jun 1, 1968·The Journal of Clinical Endocrinology and Metabolism·M W SpinnerB Childs
Jul 1, 1984·The American Journal of Medicine·D L TrenceB S Handwerger
Jan 16, 1999·Baillière's Clinical Gastroenterology·P Obermayer-Straub, M P Manns
Jan 12, 2000·Deutsche medizinische Wochenschrift·G FörsterG Kahaly
Dec 28, 2002·Springer Seminars in Immunopathology·Bart O Roep
Jul 5, 2003·The Journal of Clinical Endocrinology and Metabolism·Manuela Dittmar, George J Kahaly
May 14, 2004·The New England Journal of Medicine·George S Eisenbarth, Peter A Gottlieb
May 26, 2009·Menopause International·Svetlana Vujovic
Jun 17, 2011·The Journal of Clinical Endocrinology and Metabolism·G ReatoC Betterle
Nov 20, 2012·La Presse médicale·George J Kahaly

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