Later cART initiation in migrant men from sub-Saharan Africa without advanced HIV disease in France

PloS One
Laure-Amélie de MonteynardFrench Hospital Database on HIV

Abstract

To compare the time from entry into care for HIV infection until combination antiretroviral therapy (cART) initiation between migrants and non migrants in France, excluding late access to care. Antiretroviral-naïve HIV-1-infected individuals newly enrolled in the FHDH cohort between 2002-2010, with CD4 cell counts >200/μL and no previous or current AIDS events were included. In three baseline CD4 cell count strata (200-349, 350-499, ≥ 500/μL), we examined the crude time until cART initiation within three years after enrollment according to geographic origin, and multivariable hazard ratios according to geographic origin, gender and HIV-transmission group, with adjustment for baseline age, enrollment period, region of care, plasma viral load, and HBV/HBC coinfection. Among 13338 individuals, 9605 (72.1%) were French natives (FRA), 2873 (21.4%) were migrants from sub-Saharan Africa/non-French West Indies (SSA/NFW), and 860 (6.5%) were migrants from other countries. Kaplan-Meier probabilities of cART initiation were significantly lower in SSA/NFW than in FRA individuals throughout the study period, regardless of the baseline CD4 stratum. After adjustment, the likelihood of cART initiation was respectively 15% (95%CI, 1-28) and 20%...Continue Reading

References

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Feb 20, 2014·International Journal of Epidemiology·Murielle Mary-KrauseDominique Costagliola

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Citations

Nov 10, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A SaracinoUNKNOWN ICONA Foundation Study Group
Jun 9, 2016·Current Opinion in HIV and AIDS·Sophie Abgrall, Julia Del Amo
Dec 7, 2018·HIV Medicine·C GateyUNKNOWN COREVIH Ile de France Est Research Group
Mar 9, 2017·AIDS·UNKNOWN Migrant Health Working Group for the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroC

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