PMID: 8608600Feb 9, 1996Paper

Lateral and axial signals involved in avian somite patterning: a role for BMP4

Cell
O PourquiéN M Le Douarin

Abstract

In vertebrates, muscles of the limbs and body wall derive from the lateral compartment of the embryonic somites, and axial muscles derive from the medial compartment. Whereas the mechanisms that direct patterning of somites along the dorsoventral axis are beginning to be understood, little is known about the tissue interactions and signaling molecules that direct somite patterning along the mediolateral axis. We report the identification of a specific marker for the lateral somitic compartment and its early derivatives, cSim1, an avian homolog of the Drosophila single minded gene. Using this marker, we provide evidence that specification of the lateral somitic lineage results from the antagonistic actions of a diffusible medializing signal from the neural tube and a diffusible lateralizing signal from the lateral plate mesoderm, and we implicate bone morphogenetic protein 4(BMP4) in directing this lateralization.

References

Mar 30, 1977·Anatomy and Embryology·B ChristM Jacob
Apr 1, 1992·Trends in Genetics : TIG·M Buckingham
Oct 1, 1992·Anatomy and Embryology·B ChristJ Wilting
Jan 1, 1988·Anatomy and Embryology·K KaehnR E Poelmann
Sep 26, 1995·Proceedings of the National Academy of Sciences of the United States of America·N DahmaneJ M Delabar
Jun 29, 1995·Nature·D HenriqueD Ish-Horowicz
May 1, 1995·Anatomy and Embryology·B Christ, C P Ordahl
May 1, 1995·Nature Genetics·H ChenS Minoshima
Apr 11, 1995·Proceedings of the National Academy of Sciences of the United States of America·O PourquiéN M Le Douarin
May 5, 1995·Cell·R L Johnson, C Tabin
Sep 1, 1993·Anatomy and Embryology·B Brand-SaberiB Christ
Jun 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·O PourquiéN M Le Douarin

❮ Previous
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Citations

Dec 1, 1996·Developmental Dynamics : an Official Publication of the American Association of Anatomists·N E BlockJ B Miller
Oct 23, 1997·Developmental Dynamics : an Official Publication of the American Association of Anatomists·F CecconiP Gruss
Dec 6, 1997·Developmental Dynamics : an Official Publication of the American Association of Anatomists·S GarelP Charnay
Sep 11, 1998·Developmental Dynamics : an Official Publication of the American Association of Anatomists·G D PanopoulouN D Holland
Oct 27, 1999·Developmental Dynamics : an Official Publication of the American Association of Anatomists·D M NodenC P Emerson
Dec 11, 1999·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A DickM Hammerschmidt
Mar 8, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A Raatikainen-AhokasH Sariola
Oct 14, 1998·Developmental Genetics·K H LeeL I Zon
Jan 10, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·José L Mullor, Ariel Ruiz i Altaba
Nov 28, 2002·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Craig S Newman, Paul A Krieg
Apr 18, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·C SchmidtK Patel
Mar 3, 2005·Anatomy and Embryology·Christoph HornikErnst-Martin Füchtbauer
Sep 16, 2006·Anatomy and Embryology·Elena Vasyutina, Carmen Birchmeier
Oct 7, 2006·Anatomy and Embryology·Faisal Yusuf, Beate Brand-Saberi
Sep 29, 2006·Anatomy and Embryology·Ruijin HuangKetan Patel
Oct 7, 2006·Anatomy and Embryology·P Geetha-LoganathanB Christ
Jun 1, 1996·Trends in Genetics : TIG·G CossuM Buckingham
Mar 21, 2003·Developmental Biology·Elaine ReesDarrell J R Evans
Jun 19, 2003·Developmental Biology·Maya KumarAnne Grapin-Botton
Jun 5, 2002·Journal of Biotechnology·Elise DargelosPatrick Cottin
Aug 29, 1998·Molecular and Cellular Endocrinology·E HirsingerO Pourquié
Nov 8, 2001·Current Opinion in Cell Biology·P BaileyA B Lassar
Aug 1, 1996·Current Opinion in Genetics & Development·J D Molkentin, E N Olson
Mar 11, 1999·Current Opinion in Neurobiology·S M Hughes, P C Salinas
Nov 13, 2001·Developmental Cell·F V MarianiR M Harland
Feb 18, 2003·Journal of Anatomy·Philippa H Francis-WestKelly Anakwe
Oct 23, 2013·The Journal of Cell Biology·Catherine E WinbanksPaul Gregorevic
Aug 10, 2000·Molecular Biology of the Cell·M MerianeC Gauthier-Rouvière
Dec 18, 2001·The EMBO Journal·D Mennerich, T Braun
Sep 26, 1997·Genes & Development·C S BlagdenS M Hughes
Jan 1, 2004·Genes & Development·Eldad TzahorAndrew B Lassar
Jan 10, 2002·Genes & Development·Marcus K GustafssonCharles P Emerson
Aug 1, 1996·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Y TakahashiA Nifuji
Jul 7, 1999·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·K Choi
Jan 1, 1997·Annual Review of Cell and Developmental Biology·R Harland, J Gerhart

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