Lateral superior olive projections to the inferior colliculus in normal and unilaterally deafened ferrets

The Journal of Comparative Neurology
D R MooreN C Cathcart

Abstract

We have examined the projection from the lateral superior olive (LSO) to the inferior colliculus (IC) in the ferret, with particular interest in the laterality of the projection and in the effects of unilateral cochlear removal in infancy. Large or small deposits of the retrograde tracer wheat germ agglutinin-horseradish peroxidase (WGA-HRP) were made in the IC of anesthetized adult ferrets that either were normally hearing or had been unilaterally deafened in infancy (P5 or P25). After 2 days, the ferrets were perfused, and frontal sections of the brainstem were treated with tetramethyl benzidine. For large deposits of WGA-HRP, equal numbers of labelled neurons were found evenly spread through both LSOs. Smaller deposits of WGA-HRP produced four results that contrasted with previous reports on the cat. First, many more labelled neurons were found in the contralateral than in the ipsilateral LSO. Second, the relative number of labelled neurons in each LSO was independent of whether the deposits were in the ventral or in the dorsal IC. Third, the total number of labelled LSO neurons was independent of whether the deposits were in the ventral or in the dorsal IC. Fourth, the proportion of ipsilateral to contralateral labelled neu...Continue Reading

References

Dec 15, 1978·The Journal of Comparative Neurology·G L RothM M Merzenich
Feb 1, 1979·The Journal of Comparative Neurology·J C Adams
May 1, 1992·The Journal of Comparative Neurology·K K GlendenningR B Masterton
Jul 22, 1992·The Journal of Comparative Neurology·D H SanesJ Wardlow
Sep 1, 1991·Journal of Neurophysiology·E CoveyJ H Casseday
Mar 1, 1991·Journal of Neurophysiology·P G Finlayson, D M Caspary
Jan 1, 1990·Journal of Neurobiology·E W RubelD Durham
Mar 15, 1988·The Journal of Comparative Neurology·D R Moore
May 22, 1989·The Journal of Comparative Neurology·G T Hashisaki, E W Rubel
Jan 15, 1989·The Journal of Comparative Neurology·R L Saint MarieR J Wenthold
May 1, 1987·The Annals of Otology, Rhinology, and Laryngology·D L TucciE W Rubel
Aug 8, 1987·The Journal of Comparative Neurology·J R Coleman, W J Clerici
Feb 20, 1983·The Journal of Comparative Neurology·K W NordeenL M Kitzes
Jun 13, 1983·Brain Research·D R MooreP D Addison
May 1, 1982·The Journal of Comparative Neurology·J M Zook, J H Casseday
Jun 1, 1982·Journal of Neurophysiology·W M Jenkins, R B Masterton
Apr 20, 1981·The Journal of Comparative Neurology·J K Brunso-BechtoldR B Masterton
Jan 1, 1993·Progress in Brain Research·D R MooreM E Hutchings
Feb 8, 1993·The Journal of Comparative Neurology·K Kandler, E Friauf
May 22, 1993·The Journal of Comparative Neurology·C K Henkel, J K Brunso-Bechtold
Jun 1, 1953·The Journal of Comparative Neurology·W A STOTLER

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Citations

Dec 13, 2012·Brain : a Journal of Neurology·Andrej KralJochen Tillein
Feb 3, 2004·The Journal of Comparative Neurology·Juan Carlos AlvaradoJudy K Brunso-Bechtold
Aug 12, 1999·The Journal of Comparative Neurology·R B IllingR Laszig
Nov 29, 2007·The Journal of Comparative Neurology·Monique YoussoufianBruce Walmsley

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