Lateral Ventricle Volume Asymmetry Predicts Midline Shift in Severe Traumatic Brain Injury

Journal of Neurotrauma
Arnold TóthSteven A Robicsek

Abstract

Midline shift following severe traumatic brain injury (sTBI) detected on computed tomography (CT) scans is an established predictor of poor outcome. We hypothesized that lateral ventricular volume (LVV) asymmetry is an earlier sign of developing asymmetric intracranial pathology than midline shift. This retrospective analysis was performed on data from 84 adults with blunt sTBI requiring a ventriculostomy who presented to a Level I trauma center. Seventy-six patients underwent serial CTs within 3 h and an average of three scans within the first 10 d of sTBI. Left and right LVVs were quantified by computer-assisted manual volumetric measurements. LVV ratios (LVR) were determined on the admission CT to evaluate ventricular asymmetry. The relationship between the admission LVR value and subsequent midline shift development was tested using receiver operating characteristic (ROC) analysis, and odds ratio (OR) and relative risk tests. Sixty patients had no >5 mm midline shift on the initial admission scan. Of these, 15 patients developed it subsequently (16 patients already had >5 mm midline shift on admission scans). For >5 mm midline shift development, admission LVR of >1.67 was shown to have a sensitivity of 73.3% and a specifici...Continue Reading

References

Oct 1, 1978·Seminars in Nuclear Medicine·C E Metz
Dec 1, 1995·Computer Methods and Programs in Biomedicine·F SchoonjansF H Comhaire
Sep 27, 2003·Epilepsia·John Bruns, W Allen Hauser
Jun 3, 2004·JAMA : the Journal of the American Medical Association·Thomas B Cole
Nov 10, 2004·Journal of Digital Imaging·Antoine RossetOsman Ratib
Sep 19, 2009·The Journal of International Medical Research·G W ZhuW G Liu
Jan 29, 2011·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Jane J Kim, Alisa D Gean
Sep 23, 2014·Journal of Neurosurgery·Pedro A GómezAlfonso Lagares

❮ Previous
Next ❯

Citations

Jun 1, 2018·International Journal of Biomedical Imaging·Chun-Chih LiaoFuren Xiao

❮ Previous
Next ❯

Software Mentioned

[UNK]
MedCalc
Imaging Software

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.