Lateral visual field stimulation reveals extrastriate cortical activation in the contralateral hemisphere: an fMRI study

Psychiatry Research
Fredric SchifferMichael Rohan

Abstract

We examined whether lateral visual field stimulation (LSTM) could activate contralateral extrastriate cortical areas as predicted by a large experimental literature. We asked seven unscreened, control subjects to wear glasses designed to allow vision out of either the left (LVF) or right lateral visual field (RVF) depending upon which side the subject looked toward. Each subject participated in a block design functional magnetic resonance imaging (fMRI) study with alternating 30-s epochs in which he was asked to look to one side and then the other for a total of five epochs. On each side of the bore of the scanner, we taped a photograph for the subject to view in the LVF and RVF. The data were analyzed with SPM99 using a fixed effect, box-car design with contrasts for the LVF and the RVF conditions. Both LVF and RVF conditions produced the strongest fMRI activation in the contralateral occipitotemporal and posterior parietal areas as well as the contralateral dorsolateral prefrontal cortex. LSTM appears to increase contralateral fMRI activation in striate and extrastriate cortical areas as predicted by earlier studies reporting differential cognitive and/or emotional effects from unilateral sensory or motor stimulation.

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Citations

Jul 8, 2014·Brain and Cognition·Christophe Carlei, Dirk Kerzel
Sep 20, 2006·Journal of the International Neuropsychological Society : JINS·Valeria DragoKenneth M Heilman
Nov 9, 2011·Brain and Cognition·Ruth E PropperAshley Januszewskia
Sep 1, 2011·The Journal of Nervous and Mental Disease·Ruth E PropperTad T Brunyé
Dec 15, 2006·The International Journal of Eating Disorders·Stephen D ChristmanChristopher L Niebauer
Apr 27, 2017·Cerebral Cortex·Méadhbh B BrosnanIris Wiegand
Aug 28, 2021·Frontiers in Psychiatry·Fredric SchifferMartin H Teicher

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