Laterality of Poststroke Cortical Motor Activity during Action Observation Is Related to Hemispheric Dominance

Neural Plasticity
Sook-Lei LiewLisa Aziz-Zadeh

Abstract

Increased activity in the lesioned hemisphere has been related to improved poststroke motor recovery. However, the role of the dominant hemisphere-and its relationship to activity in the lesioned hemisphere-has not been widely explored. Here, we examined whether the dominant hemisphere drives the lateralization of brain activity after stroke and whether this changes based on if the lesioned hemisphere is the dominant hemisphere or not. We used fMRI to compare cortical motor activity in the action observation network (AON), motor-related regions that are active both during the observation and execution of an action, in 36 left hemisphere dominant individuals. Twelve individuals had nondominant, right hemisphere stroke, twelve had dominant, left-hemisphere stroke, and twelve were healthy age-matched controls. We previously found that individuals with left dominant stroke show greater ipsilesional activity during action observation. Here, we examined if individuals with nondominant, right hemisphere stroke also showed greater lateralized activity in the ipsilesional, right hemisphere or in the dominant, left hemisphere and compared these results with those of individuals with dominant, left hemisphere stroke. We found that individ...Continue Reading

References

Dec 1, 1996·Current Opinion in Neurobiology·K Y Haaland, D L Harrington
Mar 4, 2000·Stroke; a Journal of Cerebral Circulation·R S MarshallR L DeLaPaz
Jul 7, 2001·Stroke; a Journal of Cerebral Circulation·S L WolfA Piacentino
Aug 23, 2001·Medical Image Analysis·M Jenkinson, S Smith
Sep 25, 2001·Behavioural Neurology·Chris Rorden, Matthew Brett
Nov 15, 2001·NeuroImage·M W WoolrichS M Smith
Apr 27, 2002·Experimental Brain Research·Lisa Aziz-ZadehMarco Iacoboni
May 30, 2002·Neuroscience and Biobehavioral Reviews·Geoffrey Hammond
Oct 23, 2002·Human Brain Mapping·Stephen M Smith
May 24, 2003·Brain : a Journal of Neurology·N S WardR S J Frackowiak
Oct 2, 2003·Annals of Neurology·Konrad J WerhahnLeonardo G Cohen
Oct 22, 2003·NeuroImage·Christian F BeckmannStephen M Smith
Mar 31, 2004·NeuroImage·Mark W WoolrichStephen M Smith
Jun 26, 2004·Annual Review of Neuroscience·Giacomo Rizzolatti, Laila Craighero
Dec 15, 2004·Archives of Neurology·Nick S Ward, Leonardo G Cohen
Sep 9, 2005·Neuroreport·Felipe FregniAlvaro Pascual-Leone
Oct 29, 2005·Stroke; a Journal of Cerebral Circulation·Naoyuki TakeuchiKatsunori Ikoma
Jan 20, 2006·Brain : a Journal of Neurology·Nick S WardRichard S J Frackowiak
Mar 17, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Lisa Aziz-ZadehMarco Iacoboni
Oct 17, 2006·Journal of Rehabilitation Research and Development·Robert L Sainburg, Susan V Duff
Nov 7, 2006·Current Opinion in Neurobiology·Randolph J Nudo
Jun 15, 2007·Journal of Neurologic Physical Therapy : JNPT·Catherine E LangAlexander W Dromerick
Jul 13, 2007·Brain : a Journal of Neurology·Sydney Y SchaeferRobert L Sainburg
Apr 12, 2008·Stroke; a Journal of Cerebral Circulation·Pablo CelnikLeonardo G Cohen
Apr 15, 2008·NeuroImage·Mark Woolrich
Jan 9, 2010·NeuroImage·Svenja CaspersSimon B Eickhoff
Feb 6, 2010·NeuroImage·Monia CabinioGabriella Cerri
Mar 9, 2010·Neurorehabilitation and Neural Repair·Kathleen A GarrisonLisa Aziz-Zadeh
Dec 18, 2010·Stroke; a Journal of Cerebral Circulation·Jeff D RileySteven C Cramer
Jan 30, 2013·Brain : a Journal of Neurology·Saandeep ManiRobert L Sainburg
May 25, 2013·PloS One·Nadine DierschSimone Schütz-Bosbach
Jun 8, 2013·Stroke; a Journal of Cerebral Circulation·Kathleen Alice GarrisonCarolee Joyce Winstein
Aug 28, 2013·Neurorehabilitation and Neural Repair·Simone SarassoSteven L Small
Jun 27, 2014·BioMed Research International·Patrizio SaleMarco Franceschini
Jul 16, 2014·Frontiers in Human Neuroscience·Sook-Lei LiewLeonardo G Cohen

❮ Previous
Next ❯

Citations

Jul 30, 2019·Stroke Research and Treatment·Takeshi Fuchigami, Shu Morioka
Apr 29, 2021·Neuroscience and Biobehavioral Reviews·Giacomo RizzolattiPietro Avanzini

❮ Previous
Next ❯

Software Mentioned

MCFLIRT
FSL FMRIB
Featquery FSL
BET
FSL
FEAT ( FMRI Expert Analysis Tool )
MRIcron
Fslstats
FLIRT
fslmaths

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Agnes FlöelStefan Knecht
The American Journal of Psychiatry
R G RobinsonT Price
© 2022 Meta ULC. All rights reserved