Latest advances towards the discovery of 5-HT(7) receptor ligands

Mini Reviews in Medicinal Chemistry
Valeria Pittalà, D Pittala

Abstract

The 5-HT(7)receptor (5-HT(7)R), characterized in 1993, is the most recently described member of the serotonin family. Since its discovery, 5-HT(7)R has been the subject of extensive research due to its widespread distribution in the brain, suggestive of multiple central roles. The focus of this review is to illustrate the literature concerning developments of the last few years (2007-2010) towards the discovery of novel and selective 5-HT(7)R ligands, agonists, antagonist and inverse agonists.

Citations

Feb 18, 2014·European Journal of Medicinal Chemistry·Charlène SagnesBenoît Joseph
Jul 30, 2014·Journal of Medicinal Chemistry·Rocío A MedinaMaría L López-Rodríguez
Mar 17, 2015·ChemMedChem·Dawid WarszyckiAndrzej J Bojarski
Apr 29, 2015·European Journal of Pharmacology·Ozgur YesilyurtAhmet Dogrul
Jul 31, 2014·Psychopharmacology·A MenesesM Leopoldo
Feb 17, 2018·ChemMedChem·Ali AtesCéline Vermeiren
May 17, 2018·Journal of Medicinal Chemistry·Maria N ModicaMarcello Leopoldo

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